两种3,5-二氨基苯甲酰氨基脂肪酸的合成与表征  

Synthesis and Characterization of Two 3,5-Diaminobenzoylamido Fatty Acid

作　　者：李士锋[1] 鞠军 李红[1] 聂鑫[1] 廖春泉[1] 于世钧[1] 

机构地区：[1]辽宁师范大学化学化工学院,辽宁大连116029 [2]辽宁省朝阳市工业学校,辽宁朝阳122000

出　　处：《辽宁化工》2007年第11期745-747,760,共4页Liaoning Chemical Industry

基　　金：国家自然科学基金资助项目(No:20573049)

摘　　要：以3,5-二硝基苯甲酰氯、4-氨基丁酸和11-氨基十一烷酸为原料,合成了两种超支化聚酰胺AB2型单体——4-(3,5-二氨基苯甲酰氨基)丁酸和11-(3,5-二氨基苯甲酰氨基)十一烷酸。改进了含有两个硝基的羧酸类化合物还原成氨基酸类化合物的方法,采用钯炭催化加氢还原,简化了实验操作及后处理,产品收率达91.2%和93.8%。通过FT-IR、1H NMR和13C NMR对相关化合物进行了结构表征。Two AB2 monomers of hyperbranched polyamides 4 - （3 ,5 - diaminobenzoylamido） butanoic acid and 11 - （3 ,5 - diaminobenzoylamido） undecanoic acid were synthesized by 3,5 - dinitrobenzoyl chloride ,4 - aminobutyric acid and 11 - aminoundecanoic acid. The reduction of nitro acid to amino acid in the compounds with two nitros was improved through catalyzed hydrogenation with 10% Pd / C catalyst, the yields are 91.2 % and 93.8 % respectively. The experimental operation and final management were predigested. The structures of the compounds were confirmed by FT- IR,^1H NMR and ^13C NMR.

关 键 词：4-(3 5-二氨基苯甲酰氨基)丁酸 11-(3  5-二氨基苯甲酰氨基)十一烷酸 合成 表征 

分 类 号：TQ235[化学工程—有机化工]