重庆儿童急性呼吸道感染1731例病毒病原学分析  

Analysis on viral pathogen of 1731 children with acute respiratory infection in chongqing

作　　者：罗蓉[1] 黄英[1] 罗晓菊[1] 刘恩梅[1] 

机构地区：[1]重庆医科大学儿童医院呼吸科,重庆400014

出　　处：《重庆医科大学学报》2007年第12期1279-1281,1346,共4页Journal of Chongqing Medical University

摘　　要：目的:了解重庆地区儿童急性呼吸道感染(Acute respiratory infection,ARI)的病毒病原学构成,指导临床诊断与治疗。方法:对1731例住院的ARI儿童抽取鼻咽分泌物,采用直接免疫荧光法捡测7种病毒即呼吸道合胞病毒(RSV)、腺病毒、副流感病毒Ⅰ、Ⅱ、Ⅲ、流感病毒A、B。结果:儿童ARI病毒病原的总阳性率与年龄、季节及病种有关,与性别无关。7种病毒中RSV的阳性率最高,其次为副流感病毒Ⅲ。RSV在冬季、6～12月的婴儿及毛细支气管炎中感染率较高;剐流感病毒Ⅲ多见于5岁以上、上感的儿童。结论:通过检测儿童ARI的病毒病原,不仅可为临床提供快速、准确的诊断依据,防止滥用抗生素,而且为长期的病毒病原监测和病毒相关性疾病的研究奠定了基础。Objective：To investigate the viral pathogen of children with acute respiratory infection （ARI） in Chongqing and to direct clinical diagnosis and treatment. Methods：Nasopharyngeal secretion was obtained from 1731 inpatient children diagnosed as ARI,and respiratory syncytial virus（RSV）,para influenza virus Ⅰ, Ⅱ , Ⅲ ,adeno virus and influenza virus A,B were detected by direct immunofuorescence. Results：There was relationship between total positive rate of virus pathogens of children with ARI and age,season and respiratory disease,but not for sex. Among the 7 virus,top detected virus was RSV,followed in turn by para influenza virus Ⅲ. There was higher RSV detection rate in infants aged 6～12months with bronchiolitis in winter. Para influenza virus Ⅲ was commonly detected in children with upper respiratory infection and over 5 years. Conclusions：Detection of viral pathogens in children with respiratory infection could give fast,accurate diagnostic evidence,and help avoid antibiotics abuse. Moreover,it is the base of long-term detection of viral pathogens and the base of the study about the virus relative diseases.

关 键 词：儿童 急性呼吸道感染 病毒病原 

分 类 号：R373.1[医药卫生—病原生物学]