重庆地区儿童乙型肝炎病毒感染状况分析  

Analysis of the infection status of hepatitis B virus in Chongqing children

作　　者：李小强[1] 刘岚[1] 曾照芳[2] 龚曼子[1] 魏强[1] 吴扬[1] 郑玉强[1] 陈元[1] 

机构地区：[1]重庆医科大学附属儿童医院检验科,重庆400014 [2]重庆医科大学检验系,重庆400016

出　　处：《重庆医科大学学报》2007年第12期1317-1319,共3页Journal of Chongqing Medical University

摘　　要：目的:初步了解重庆地区儿童乙型肝炎病毒的感染状况。方法:对来重庆医科大学儿童医院就诊的8060例儿童用ELISA方法检测乙肝6项。结果:HBsAg阳性率为4.44%,抗-HBs阳性率为46.56%,两对半全阴性儿童3795人,占47.08%;大三阳259人,占3.21%;小三阳80人,占0.99%。Pre-S1阳性率为3.51%。结论:来我院检查的8060例儿童,乙肝病毒感染率为4.44%,低于我国成人乙肝病毒携带率;Pre-S1与HBeAg有一定相关性,能在一定程度上反映乙肝病毒增殖情况和传染性。Objective：To investigate infection status of hepatitis B virus in ChongQing children. Method：We detected the HBV serology markers（HBVM） by ELISA in 8060 children in Children＇s Hospital of Chongqing Medical University. Results：HBsAg positive rate was 4.44%,anti-HBs positive rate 46.56%. 3795 cases were negative in HBVM（47.08%）;259 cases were positive in HBsAg,HBeAg and anti-HBc（3.21%）;80 cases were positive in HBsAg, anti-HBe, anti-HBc （0.99%）,and Pre-S1 positive rate was 3.51%. Conclusion：Among the 8060 children who came to our hospital,the infection rate of HBV is 4.44%,lower than in the adults. Pre-S1 is related with HBeAg,and it can reflect the status of HBV multiplication and infectivity to some extent.

关 键 词：儿童 乙肝标志物 HBV 

分 类 号：R446.62[医药卫生—诊断学]