纳米Cu／HAP制备中四氨合铜（Ⅱ）的作用  

Actions of tetrammine copper（Ⅱ） in preparation of nanoscaled Cu/HAP with coprecipitation

作　　者：杨辉[1,2] 陈永康[1] 张林[1] 徐可为[2] 

机构地区：[1]陕西科技大学生命科学与工程学院,陕西西安710021 [2]西安交通大学金属材料强度国家重点实验室,陕西西安710049

出　　处：《功能材料》2007年第A06期2191-2194,共4页Journal of Functional Materials

基　　金：基金项目：西安市科技局重点技术攻关资助项目（GG200354）;陕西省2004年自然科学基金资助项目（2004824）陕西科技大学B类科技创新团队经费资助项目（sust-B104）

摘　　要：将[Cu（NH3）4]^2＋用于以（NH4）2HPO4和Ca（NO3）2为前体的HAP合成体系中，制备出了纳米级Cu／HAP晶体，合成反应中，[Cu（NH3）4]^2＋是铜离子的供体，又是粒子尺寸控制剂。研究了不同浓度、不同反应温度下[Cu（NH3）4]^2＋对Cu／HAP合成和晶粒尺寸的影响。结果表明：在试验浓度范围内[Cu（NH3）4]^2＋浓度越大，所得晶粒尺寸越小；Cu^2＋取代HAP晶格中的构晶离子Ca^2＋可引起HAP晶体生长习性的改变，抑制晶体沿C轴生长。[Cu（NH3）4]^2＋存在的条件下，温度升高仍然可以形成大颗粒的Cu／HAP。Nanoscaled Cu/HAP powder was prepared using tetrammine copper（Ⅱ） （[Cu（NH3）4]^2＋） in the preparation of hydroxyapatite （HAP） with the coprecipitation of calcium nitrate（Ca（NO3）2） acting with ammonium hydrogen phosphate（（NH4）2HPO4）. In preparation of Cu/HAP powder, [[Cu（NH3）4]^2＋ were both the starting material and the size-controller of the Cu/HAP crystal. The effects of concentration of [Cu（NH3）4]^2＋ and the reaction temperature on the microstructure and size of the Cu/HAP crystal were investigated. The results show that the higher the concentration of [Cu（NH3）4]^2＋ within the experimental range of it, the smaller the size of the Cu/H crystal. Cu^2＋ replacing the Ca^2＋ ill the lattice of HAP can cause the change of growth tendency of the Cu/HAP crystal which makes the Cu/HAP crystal grow along the c-axis. At the presence of [Cu（NH3）4]^2＋ in preparation of HAP, the large size Cu/HAP crystal is got at high synthesis temperature.

关 键 词：四氨合铜(Ⅱ) 共沉淀 纳米材料 载铜羟基磷灰石 抗菌剂 尺寸控制 

分 类 号：R318.08[医药卫生—生物医学工程] TB34[医药卫生—基础医学]