磷酸钙在纳米羟基磷灰石／硅橡胶复合材料表面的仿生合成  

Biomimetic synthesis of calcium phosphate on the surfaces of nano-hydroxyapatite/silicone rubber composite

作　　者：文季秋[1] 李玉宝[1] 左弈[1] 张利[1] 廖建国[1] 李吉东[1] 

机构地区：[1]四川大学纳米生物材料研究中心、分析测试中心,四川成都610041

出　　处：《功能材料》2007年第A05期1832-1834,共3页Journal of Functional Materials

基　　金：国家重点基础研究发展计划（973计划）国际合作资助项目（中荷战略科学联盟计划项目）（2004CB720604）

摘　　要：将纳米羟基磷灰石，硅橡胶复合材料浸泡于模拟体液（SBF）中仿生合成了磷酸钙，利用IR、XRD、ICP和SEM等测试手段对表面沉积物进行表征．结果表明：在模拟体液中浸泡后，复合材料表面形成了分布均匀的以羟基磷灰石为主要成分的晶粒，表面羟基磷灰石的比例得到提高，生物学性能得以进一步改善；表明纳米羟基磷灰石，硅橡胶复合材料是一种生物活性材料．Calcium phosphate was synthesized biomimeticly on the surfaces of nano-hydroxyapatite/silicone rubber composite by soaking the composite in simulated body fluid （SBF）. IR, XRD, ICP and SEM were employed to characterize the precipitate on the surfaces. The results indicate that crystals have been formed on the composite surfaces homogenously after soaking the composite in SBF and these crystals are mainly hydroxyapatite. Furthermore, the ratio of hydroxyapatite on the surfaces of the composite increases and the better biological properties are expected. The results suggest that nano-hydroxyapatite/silicone rubber composite is a kind of bioactive material.

关 键 词：磷酸钙 仿生合成 羟基磷灰石 硅橡胶 复合材料 

分 类 号：R313.08[医药卫生—基础医学]