扩张型心肌病患者高血压患病率的初步调查  

Preliminary Survey on the Prevalence Rate of Hypertension in Patients with Dilated Cardiomyopathy

作　　者：曾小林[1] 杨天伦[1] 孙明[1] 马琦琳[1] 吴声滨[1] 

机构地区：[1]中南大学湘雅医院心内科,湖南省长沙市410008

出　　处：《中国动脉硬化杂志》2007年第8期638-640,共3页Chinese Journal of Arteriosclerosis

摘　　要：目的观察扩张型心肌病患者高血压患病率及其并发高血压的主要危险因素。方法随机选取扩张型心肌病患者362例及401例同年龄的普通居民(对照组),统计各组高血压患病率并作组间比较;根据患者有无合并高血压,将扩张型心肌病患者分成高血压亚组与非高血压亚组,比较两亚组患者与血压相关的临床资料有无差异。结果扩张型心肌病患者高血压患病率明显高于对照组(32.9%比21.7%,P<0.01);扩张型心肌病两亚组患者的年龄、性别、职业、左心室射血分数等因素差异无显著性(P>0.05),但高血压亚组患者的心率及高血压家族史百分率均明显高于非高血压亚组(P<0.05或P<0.01)。结论扩张型心肌病患者的高血压患病率高,交感神经系统兴奋性升高及高血压遗传因素可能是其并发高血压的主要危险因子。Aim To investigate the prevalence rate of hypertension and its primary risk factors in patients with dilated eardiomyopathy （DCM）. Methods 362 patients with DCM （DCM group）and 401 age-matched residents （control group） were enrolled randomly in the study, the hypertensive prevalence rate were calculated respectively in the two groups and was compared with each other, The patients in the DCM group were divided into two subgroups （hypertension subgroup and no-hypertension sub-group） according to whether the patients had hypertension; the clinical data relating to blood pressure were compared between the two subgroups. Restdts The pervalence rate of hypertension in DCM group was significantly higher than that in the control group （32.9% vs 21.7%, P 〈 0.01）, There were no significant differences on the age, gender, occupation and left ventricular ejection fraction （LVEF） between the two subgroups, but the mean heart rate and the percentage of patients who had hypertensive family history were significantly higher in the hypertension subgroup than that in the no-hypertension subgroup （ P 〈 0.05 or P 〈 0.01 ）. Conclusion The prevalence rate of hypertension in patients with DCM was high. The increased activity of sympathetic nervous system and the hypertensive genetic factor may be the primary risk factors of hypertension in patients with DCM.

关 键 词：内科学 扩张型心肌病 高血压 患病率 危险因子 心功能衰竭 

分 类 号：R5[医药卫生—内科学]