同型半胱氨酸与颈动脉粥样硬化关系分析  

Relationship between Serum Homocysteine Level and Carotid Artery Atherosclerosis

作　　者：梅今[1] 刘向远[1] 董贯中[1] 辛晋敏[1] 

机构地区：[1]江苏南京医科大学附属常州第二人民医院神经内科,213003

出　　处：《实用全科医学》2007年第12期1076-1077,共2页Applied Journal Of General Practice

摘　　要：目的探讨同型半胱氨酸(Hcy)水平与颈动脉硬化的相关性。方法对65例脑梗死患者与60例健康对照者进行Hcy水平的测定,并应用彩色多普勒超声进行颈动脉检测。结果脑梗死患者组比健康对照组血Hcy水平明显增高(P(0.01),颈动脉粥样硬化发生明显增多(P(0.01),同时高Hcy血症患者比正常Hcy血症者颈动脉粥样硬化发生率高(P(0.01)。结论高Hcy血症通过多种机制加速动脉粥样硬化,促进脑梗死的形成。Objective To evaluate the relationship between serum homocysteine （ Hcy ） level and carotid artery atherosclerosis. Methods The Hcy levels of 65 cases with cerebral infarction and 60 health controls were detected. The carotid artery was assayed by Doppler uhrasonography. Results The Hcy level in the patients with cerebral infarction and the incidence of atherosclerosis were higher than that in the controls （P 〈 0.01 ）. The incidence of atherosclerosis in cases with high levels of Hcy was high- er that with normal Hcy （ P 〈 0.01 ）. Conclusions High levels of Hcy in plasma can develop carotid atherosclerosis and promote the formation of cerebral infarction through varieties of mechanisms.

关 键 词：同型半胱氨酸 颈动脉粥样硬化 

分 类 号：R543.4[医药卫生—心血管疾病]