二乙氧基磷酰化香豆素的合成与表征  

Synthesis of phosphoryl coumarins by atheron-todd reaction

作　　者：武现丽[1] 赵军峰[1] 荣垂林[1] 廖新成[1] 

机构地区：[1]郑州大学化学系化学生物实验室,河南郑州450052

出　　处：《化学研究与应用》2007年第7期806-808,共3页Chemical Research and Application

摘　　要：Six kinds of phosphorylated coumarins are successfully synthesized by an Atherton-Todd reaction. They are fully characterized by FTIR、1H NMR、31P NMR、ESI-MS and EA. For the 6,7-dihydroxy coumarin, there was selective phosphorylation in the 6-hydroxyl group in the reaction. XRD analysis of 2f is described. The crystal is nomoclinic, space group P2(1)/n. there is hydrogen-bonding interaction between O atom on P=O and H atom on O-H.Six kinds of phosphorylated coumarins are successfully synthesized by an Atherton-Todd reaction. They are fully characterized by F17R,^1H NMR,^31P NMR,ESI-MS and EA. For the 6,7-dihydroxy coumarin, there was selective phosphorylation in the 6-hydroxyl group in the reaction. XRD analysis of 2f is described. The crystal is nomoclinic, space group P2（1）/n. there is hydrogen-bonding interaction between O atom on P = O and H atom on O-H.

关 键 词：Atherton-Todd反应 香豆素 磷酰化 

分 类 号：O629.5[理学—有机化学]