微波辐射下双(2-苯并咪唑基)丙烷的合成与结构表征  

Synthesis and characterization of bis(2-benzimidazolyl) propane under microwave irradiation

作　　者：吕维忠[1] 刘波[1] 韦少慧[1] 高原[1] 刘剑洪[1] 

机构地区：[1]深圳大学化学与化工学院,广东深圳518060

出　　处：《化学研究与应用》2007年第7期817-819,共3页Chemical Research and Application

摘　　要：Bis(2-benzimidazolyl)propane was synthesized by the reaction of o-phenylenediamine and glutaric acid which was accelerated by microwave irradiation and catalyzed by poly phosphoric acid(PPA) under solvent-free condition. By the method of orthogonal experiment optimize synthesis factors which affect the reation: o-Phenylent Diamine: glutaric acid:2.2∶1.0(mol:mol),PPA:9.0g,time of microwave irradiation:8min, and the power of microwave irradiation:160W. Under the optimal condition, the highest yield of Bis(2-benzimidazolyl) propane is 77.4%. The products were characterized by melting point determination, IR spectrogram,1HNMR spectra and 13CNMR spectra.Bis （2-benzimidazolyl）propane was synthesized by the reaction of o-phenylenediamine and glutaric acid which was accelerated by microwave irradiation and catalyzed by poly phosphoric acid（PPA） under solvent-free condition. By the method of orthogonal experiment optimize synthesis factors which affect the reation： o-Phenylent Diamine： glutaric acid：2.2： 1.0（mol：mol） ,PPA： 9.0g,time of microwave irradiation ：Smin, and the power of microwave irradiation：160W. Under the optimal condition, the highest yield of Bis（2-benzimidazolyl） propane is 77.4%. The products were characterized by melting point determination, IR spectrogram, ^1HNMR spectra and ^13CNMR spectra.

关 键 词：微波辐射 合成 双(2-苯并咪唑基)丙烷 正交实验 优化 

分 类 号：O625.25[理学—有机化学]