巴氯芬结合运动疗法对颅脑外伤后偏瘫患者肌痉挛的疗效观察  

Effect of Baclofen and Physical Therapy on Spasticity after Cerebral Traumatic Injury

作　　者：尹清[1] 汪琴[1] 刘青山[1] 王濮[1] 刘宏亮[1] 

机构地区：[1]第三军医大学西南医院康复科,重庆市400038

出　　处：《中国康复理论与实践》2007年第11期1052-1053,共2页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的观察巴氯芬结合运动疗法对颅脑外伤后偏瘫患者肌痉挛的治疗效果及不良反应。方法颅脑外伤后的偏瘫住院患者20例,分别予巴氯芬口服并结合运动治疗3～6个月。服药前、服药中每2月检查1次血尿常规及肝、肾功能。按修订Ash-worth评分评定肌张力,改良的巴氏指数(MBI)评定患者日常生活活动能力。结果20例患者中显效1例(5.0%),有效9例(45.0%),好转8例(40.0%),无效2例(10.0%),总有效率为90.0%。MBI从(29.91±7.63)上升为(58.18±8.32)(P<0.01)。未见明显的毒副作用。结论巴氯芬结合运动治疗对控制颅脑外伤患者的肌痉挛有效,治疗时机以早期为宜。Objective To study the effect of baclofen and physical therapy on spasticity after cerebral traumatic injury. Methods 20 Patients accepted Baclofen and physical therapy for 3 -6 months. Blood and urine routine test, hepatic and renal function were monitored before and every 2 months after treatment. Modified Ashworth scale and Modified Barthel Index （MBI） were used for evaluation. Results Their muscular tension was significantly improved （P〈0. 01） after treatment, as well as the MBI （P〈0.01）. 1 case was very effective, 9 cases were effective, 8 cases were improved, 2 cases were not effective. No side-effect was observed. Conclusion Bactofen and physical therapy is effective on spasticity after cerebral traumatic injury, especially intervening at the early stage.

关 键 词：颅脑外伤 肌痉挛 巴氯芬 运动疗法 

分 类 号：R651.1[医药卫生—外科学]