21例造血干细胞移植术后医院感染临床分析  

Hospital Infection after Hemopoietic Stem Cell Transplantation:Clinical Analysis of 21 Cases

作　　者：张玲[1] 尚振川[1] 苏春蓉[1] 孙浩平[1] 

机构地区：[1]成都军区总医院,四川成都610083

出　　处：《中华医院感染学杂志》2007年第11期1370-1372,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析造血干细胞移植术后医院感染的发病率和高危因素,探讨其防治策略。方法回顾分析21例造血干细胞移植术后医院感染的临床资料。结果21例患者中15例发生医院感染,感染率为71.4%;检查分离出细菌15株,真菌4株;高危因素为各种侵入性操作、激素和抗菌药物的不合理应用等。结论造血干细胞移植术后医院感染发生率高、预后差,除减少各种侵入性操作、合理应用激素和抗菌药物外,关键在于早期发现与治疗,更重要的是注重全环境保护。OBJECTIVE To study the rate and the risk factors of hospital infection after hemopoietic stem cell transplantation and improve treatment strategy. METHODS The clinical data of 21 cases of hemopoietic stem cell transplantation were analyzed respectively in our hospital. RESULTS Hospital infection was found in 15 cases, the infection rate was 71.4M. Fifteen kinds of bacteria and 4 kinds of fungi were observed. The risk factors were aggressive operation, the abuse of glucocorticoid and antibiotics. CONCLUSIONS The patients have a high rate of hospital infection after hemopoietic stem cell transplantation and a poor prognosis because of hospital infection. To decrease the rate of hospital infection after hemopoietic stem cell transplantation, the whole environmental protection should be carried out except decreased aggressive operation and the correct use of glucocorticoid and antibiotics.

关 键 词：造血干细胞移植术 医院感染 病原菌 全环境保护 

分 类 号：R551[医药卫生—血液循环系统疾病]