奥曲肽治疗术后早期炎症性肠梗阻的临床研究  

Clinical study of octreotide in the treatment of early postoperative inflammatory intestinal obstruction

作　　者：黎小明[1] 黄擎雄[1] 聂剑[1] 黎小燕[1] 

机构地区：[1]肇庆市第一人民医院外科,广东省肇庆526021

出　　处：《中国基层医药》2007年第10期1626-1627,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨奥曲肽治疗术后早期炎症性肠梗阻的疗效。方法41例术后早期炎症性肠梗阻患者随机分为对照组(19例)和奥曲肽组(22例)。对照组采用常规禁食、胃肠减压、补液、维持水电解质和酸碱平衡、抗感染等传统方法治疗;治疗组在对照组采取的措施基础上,再加用奥曲肽0.1 mg,每8小时1次,连用3～10 d。结果奥曲肽组胃肠减压量在应用奥曲肽后即明显减少,临床症状缓解迅速,肛门排气时间明显提前,平均住院时间亦缩短.两组比较差异均有统计学意义。结论奥曲肽是治疗术后早期炎症性肠梗阻的一种有效药物。Objective To investigate the effect of octreotide in the treatment of early postoperative inflammatory intestinal obstruction. Methods 41 cases of early postoperative inflammatory intestinal obstruction were divided into two group： control group（19 cases） and octreotide group （22 cases）. The patients of control group were treated with fasting, gastrointestinal decompression, clysis, maintaining electrolyte and acid-base balance, anti-infection. The patients of octreotide group were treated the same as control group and octreotide（sandostatin） 0.1mg, every 8h for 3-10 days. Results In octreotide group,the quantity of gastrointestinal decompression decreased obviously, clinical symptoms relieved more quickly, the average anal exhaust time advanced obviously, the average hospitalization time also shortened, there were significant difference compared with those of control group respectively. Conclusion Oetreotide was an effective drug in the treatment of early postoperative inflammatory intestinal obstruction.

关 键 词：奥曲肽 术后 肠梗阻 

分 类 号：R656.7[医药卫生—外科学]