运动干预对饮食性高胆固醇血症大鼠肝脂肪变的影响  

Effect of Exercise Treatment on Fatty Liver in Diet - induced Hypercholesterolemia Rats

作　　者：赵肖宪[1,2] 颜宜苣[1,2] 傅小锁 张勇[1,2] 杨锡让 

机构地区：[1]北京职工医学院生理教研室 [2]北京体育大学运动生理教研室

出　　处：《中国运动医学杂志》1997年第3期186-188,共3页Chinese Journal of Sports Medicine

基　　金：健力宝"运动医学青年科研基金

摘　　要：以高脂膳食诱导ＳＤ大鼠高胆固醇血症，观察了血清ＴＣ、ＴＧ和ＬＤＬ－Ｃ水平变化及肝脏脂肪变以及有氧运动干预对其的影响。结果表明，ＳＤ大鼠血清ＴＣ和ＬＤＬ－Ｃ水平显著提高，ＴＧ未呈显著性改变；普通病理学观察肝细胞呈明显脂肪病变，超微形态观察肝组织亚细胞结构损伤；８周有氧运动干预显著降低高胆固醇血症大鼠血清ＴＣ、ＴＧ和ＬＤＬ－Ｃ水平，明显改善肝脂肪变程度，研究提示，有氧运动对脂肪肝有明显的预防和治疗作用。The change of serum lipid , the fat accumulation in hepatic cells and the effect of aerobic exercise on these alter- ations were evaluated by using the experimental model of hypercholesterolemia in rats . The results showed that the high lipid diet induced hypercholesterolemia and fatty liver . Aerobic exercise markedly decreased the levels of serum choles- terosis ,triglyceride and low density lipoprotein , and improved hepatic pathogenesis in fat accumulation . The result sug- gested that the aerobic exercise may play a positive role in prevention and cure of fatty liver .

关 键 词：高胆固醇血症 脂肪肝 有氧运动 大鼠 膳食 

分 类 号：R87[医药卫生—运动医学] R589.202[医药卫生—临床医学]