解脲支原体分群分型在妇女非淋菌性尿道炎诊断中的应用  

Investigate on the infection of Ureaplasma urealyticum (Uu) in woman nongonococcal urethritis (NGU) population and its biovars and serotypes

作　　者：徐小平[1] 李卓成[1] 艾辉[1] 严冰[1] 

机构地区：[1]广东省深圳市第二人民医院检验科,广东深圳518035

出　　处：《中国现代医学杂志》2007年第21期2647-2650,共4页China Journal of Modern Medicine

基　　金：深圳市科技信息局资助项目(No:200405132)

摘　　要：目的探讨解脲支原体(Uu)分群分型在妇女非淋菌性尿道炎(NGU)诊断中的价值。方法采用PCR、DNA测序技术对Uu进行分群分型。结果经液体培养Uu阳性的177例中,采用PCR法检测Uu阳性为105例(59.3%),其中试验组(68例)生物1群感染54例(79.4%),生物2群感染13例(19.1%),生物1群和生物2群混合感染1例(1.5%),分布于14个血清型。结论Uu感染与寄居均以生物1群为主,而生物2群中的血清4型与妇女NGU发生具有显著相关。[Objective] To investigate the infection of Ureaplasma urealyticum （Uu） in woman nongonococcal urethrifts （NGU） population and its biovars and serotypes. [Methods] The technique of culture isolation and molecular biology were used to study different serotypes of Uu infection in cervical specimens taken from NGU patients and gynecologic check-up persons in Shenzhen regions. [Results] 177 cases were screened to be Uu positive by liquid culture and 105 cases were found to be Uu positive by PCR method （59.3%）. In Uu positive 68 cases of the test group, 54 were Parvum biovar （79.4%）, 13 were Urealyficum biovar （19.1%） and the nfixed infections of these two biovars were 1 cases （1.5%）. [ Conclusion] The majority of Uu cervical colonization and pathogenesis was Parvum biovar, moreover, serotype 4 of Urealyficum biovar was the one most frequently found and strongly related with woman NGU.

关 键 词：解脲支原体 生物群 血清型 非淋菌性尿道炎 

分 类 号：R695.1[医药卫生—泌尿科学]