二硫化碳接触者肾功能损伤早期监测指标评价  被引量:1

Assessment of Early Biomarker of Renal Damage of Workers Exposed Chronically to Carbon Disulfide

在线阅读下载全文

作  者:马林[1] 张桥[1] 杨杏芬[1] 陈铁江[1] 吴大伟[1] 陈德明 

机构地区:[1]中山医科大学卫生学院 [2]广东省韶关市职业病防治院

出  处:《中国公共卫生学报》1997年第3期170-171,共2页

摘  要:通过对某化纤厂71名二硫化碳作业工人调查发现,二硫化碳接触工人尿β2-MG和LDH显著高于对照组,且随暴露二硫化碳浓度增高,工龄延长而升高,呈剂量-反应关系。AKP和ALb则在高浓度组和高工龄段显著高于对照组。表明尿β2-MG和LDH可作为慢性二硫化碳接触者肾功能损伤的早期监测指标。71 workers exposed to carbon disulfide in a rayon factory and 31 unexposed health workers as controls were investigated.The results showed the levels of urinaria β 2 microglobulin(β 2 MG) and lactate dehydrogenase(LDH) in the exposed group were significantly higher than that of control group,and increased progressively with increasing concentration of carbon disulfide and working years;but alkaline phosphatase (AKP) and albumin(Alb) in high concentration and working year of expoesd group were higher significantly than that of control.That indicated the β 2 MG and LDH may be early biomarkers of renal lesion in chronic carbon disulfide workers.

关 键 词:二硫化碳 尿酶 尿Β2-MG 肾功能损伤 

分 类 号:R135.1[医药卫生—劳动卫生] R114[医药卫生—公共卫生与预防医学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象