胰岛素样生长因子结合蛋白-1与宫颈Bishop评分在预测临产中的比较  

Comparison of the Insulin-like Growth Factor-binding Protein-1 and the Cervical Bishop Score in Predicting the Onset of Delivery

作　　者：宋玉琳[1] 金明华[1] 

机构地区：[1]湖南省妇幼保健院妇产科,湖南长沙410008

出　　处：《医学临床研究》2007年第6期948-949,共2页Journal of Clinical Research

摘　　要：【目的】研究胰岛素样生长因子结合蛋白-1(GFBP-1)在预测临产时间中的临床意义。【方法】对84例初产妇,采用检测阴道分泌物GFBP-1的阳性率和宫颈Bishop评分来预测一周内临产的成功性。【结果】宫颈Bishop评分≥7分者IGFBP-1阳性率为91.67%,明显高于<7分者47.91%(P<0.001)。67例一周内临产者中IGFBP-1阳性51例(76.12%),IGFBP-1阴性16例(23.88%),两者差异有显著性(P<0.001)。且随着宫颈成熟度的增加,IGFBP-1阳性率逐渐升高,IGFBP-1阳性率与宫颈成熟度呈正相关。【结论】检测阴道泌物中IGFBP-l预测临产时间明显优于宫颈评分,其阳性可预测在一周内临产。【Objective】To study the clinical significance of insulin-like growth factor-binding protein-1（IGFBP-1）in predicting the onset of delivery.【Methods】The successful predictal rate of the onset of delivery within one week through determining IGFBP-1 in vaginal secretion and the cervical Bishop score（CBS） of 84 primiparae was evaluated.【Results】The cervix Bishop score being equal to or over 7,the positive percentage of IGFBP-1 was 91.67%;and the cervical Bishop score being below 7,the positive percentage of IGFBP-1 was 47.91%,the difference was significant.Among 67 cases of the onset of delivery within one week,there were 51 cases IGFBP-1 being positive,and the percentage was 76.12%;there were 16 cases IGFBP-1 being negative,and the percentage was 23.88%,the difference was significant.As cervix maturity degree increased the positive percentage of IGFBP-1 was rising gradually,and both were apparently correlative.【Conclusion】Determining IGFBP-1 in vaginal secretion is better obviously than using cervical Bishop score in predicting the onset of delivery,and the positive IGFBP-1 could predict the onset of delivery within one week.

关 键 词：胰岛素样生长因子结合蛋白质1 子宫颈 分娩 

分 类 号：R714.3[医药卫生—妇产科学]