应用昆虫毒素基因构建重组病毒杀虫剂研究进展  

Advances in insect-specific toxin genes for recombinant insect virus

作　　者：蒋洪[1] 韩亚娟[2] 张珈敏[2] 胡远扬[2] 

机构地区：[1]武汉大学病毒学国家重点实验室环球生物农药武汉大学联合研发中心,武汉430072 [2]武汉大学基础医学院病原生物学系,武汉430072

出　　处：《植物保护》2007年第6期1-5,共5页Plant Protection

基　　金：国家自然科学基金(30370962)

摘　　要：由于基因工程技术的发展和安全性研究的深入,以重组杆状病毒为主的重组昆虫病毒杀虫剂的应用正面临着突破。文章综述了通过插入昆虫专一性毒素基因构建重组昆虫病毒杀虫剂的技术路线,展望重组病毒杀虫剂的发展趋势。Biological control of agricultural and urban pests has gained importance in recent years due to increased pressure to reduce the use of chemical insecticides and their residues in the environment and food. Insect viruses are valuable natural control agents and they have been genetically modified to improve their insecticidal activity. There are two major strategies at present, in a broad sense, for improving the timing of killing action of these agents, i. e. interference with host physiology and introduction of an insect-specific toxin. Recombinant insect viruses are efficacious in the laboratory, greenhouse and field trials. Hopefully, the negative influence of social perception of genetically modified organisms on biotechnological research will gradually decrease and recombinant insect viruses will be introduced as an important biological factor in the near future.

关 键 词：昆虫毒素基因 重组病毒杀虫剂 杆状病毒 生物防治 

分 类 号：S859.795[农业科学—临床兽医学]