正交设计法优选壬苯醇醚膜剂的制备工艺  

Study of the Prepartion Technique of Nonoxyolum Films by Orthogonal Design Method

作　　者：姚丹[1] 谢成国[1] 

机构地区：[1]辽宁医学院,锦州121001

出　　处：《数理医药学杂志》2007年第6期878-879,共2页Journal of Mathematical Medicine

摘　　要：目的:优选壬苯醇醚膜剂的最佳处方。方法:以膜剂外观和融解时间为指标,采用L9(34)正交试验筛选处方。结果:膜剂最加处方为:CMC-Na 3.0 g,水80ml,甘油4g,PVA17881.25g。结论:膜剂的外观和融解时间指标符合质量标准要求,优选出的制备工艺经验可行、可靠。Objective： To optimize the formulation of Nonoxyolum Films. Methods： With the exterior quality and melting time as indexes, orthogonal design was used to select the formulation of the films. Results： The optimun formulation was CMC-Na 3. 0 g, water 80ml, glycerine 4g and PVA1788 1.25g. Conclusion： The exterior and melting time of the films are meet the requirements of qulaity standard. The optimal preparation technique is satisfactory and reliable by test and verify.

关 键 词：壬苯酵醚膜剂 正交设计法 制备工艺 

分 类 号：R911[医药卫生—药学]