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作 者:马静[1] 黄春香[1] 皮丕湘[2] 夏爱斌[3]
机构地区:[1]中南大学湘雅二医院精神卫生研究所,长沙410011 [2]中南大学湘雅二医院妇产科,长沙410011 [3]长沙市妇幼保健院妇产科,长沙410011
出 处:《实用儿科临床杂志》2007年第3期223-224,共2页Journal of Applied Clinical Pediatrics
基 金:国家自然科学基金项目资助(30470620)
摘 要:目的研究婴儿气质与其出生时脐血CD4^+、CD8^+淋巴细胞百分数、绝对计数及CD4^+/CD8^+间的关系。方法取25例健康新生儿脐带血,采用流式细胞检测技术测CD4^+、CD8^+淋巴细胞百分数并计算绝对计数及CD4^+/CD8^+值,并在婴儿1-4个月(平均2.52个月)时,使用Carey小婴儿气质问卷(EITQ)及气质分析软件对气质的9个维度分别进行评分。结果CD4^+淋巴细胞百分数与小婴儿气质维度中的坚持性存在负直线相关关系(r=-0.43P=0.033);CD8^+淋巴细胞百分数、CD4^+及CD8^+绝对计数及CD4^+/CD8^+值与小婴儿气质各维度无相关关系。结论婴儿气质与CD4^+淋巴细胞百分数存在负相关;CD4^+淋巴细胞百分数越低,婴儿坚持性可能越好。Objective To examine whether neonate′s cord blood T-lymphocytes is related to infant temperament.Methods Twenty-five healthy babies were randomly chosen in Changsha from Jul.2005 to Aug.2005 and their cord blood was drown when they were born. CD4^+ and CD8^+ counts, CD4^+%, CD8^+%, CD4^+/ CD8^+ratios were obtained using flow cytometry analysis. Infant temperament were measured after 1-4 months( mean age 2.52 months) with parent response to carey revised infant temperament questionnaire(EITQ/RITQ) administered.Results The percentage of CD4^+ T-cell subsets to total lymphocytes correlated negatively with persistence scores (r=-0.43 P=0.033). However, CD8^+%, CD8^+ and CD4^+ counts, CD4^+/ CD8^+ ratios were not correlated with temperament traits.Conclusions The lower CD4 %, the better infants' persistence.
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