压电传感实时监测氯霉素分子印迹聚合物的原位合成  

Investigation on the In-situ Synthesis of Molecular Imprint Polymer for On-line Monintoring Chloromycetin by Piezoelectricity Sensor

作　　者：吴永强[1] 

机构地区：[1]四川理工学院材料与化学工程系,四川自贡643033

出　　处：《压电与声光》2007年第6期660-662,共3页Piezoelectrics & Acoustooptics

基　　金：四川省教育厅重点资助项目(2003A134);国家十五科技攻关资助项目:食品安全关键技术的研究

摘　　要：氯霉素是一种广谱抗菌药物,但食物中的氯霉素残留物质对人类的健康构成了巨大威胁。该问题已引起国际组织和世界上许多国家和地区的高度重视。通过压电传感器检测残余的氯霉素,具有无需适用放射性材料和预处理时间短的优势。因此,合成人工模拟单克抗体——氯霉素分子印记聚合物非常有意义。实验在10μL的压电传感器的金电极上,原位合成氯霉素印迹聚合物。实验结果表明,聚合反应过程是二级反应。Chloromycetin is a type of wide spectra anti-bacteria medicine, but its remnant in the animal foodstuff imposes great threat on the human health. International organizations and many states as well as regions all over the world have attached great importance to this issue. Advantages for the monitoring the Chloromycetin remnant by piezoelectricity sensor include no need for radioactive material and short time for pretreatment. Hence, to synthesize manual simulative antibody, called molecular imprint polymer for chloromycetin, is of great importance. On the 10 μL piezoelectricity sensor electrode, molecular imprint polymer responding to chloromycetin is prepared. Experimental result indicates that imprinting polymerization reaction process is the second order reaction.

关 键 词：压电传感 分子印迹聚合物 原位 合成 模拟抗体 

分 类 号：R446.5[医药卫生—诊断学] TP212[医药卫生—临床医学]