应用Amplatzer封堵器介入治疗继发孔房间隔缺损远期疗效观察  

Long term follow-up of transactheter closure of atrial septal defect with Amplatzer occluder

作　　者：马翔[1] 马依彤[1] 杨毅宁[1] 汤宝鹏[1] 黄定[1] 刘晓[1] 穆玉明[1] 韩伟[1] 

机构地区：[1]新疆医科大学第一附属医院心血管病专科医院,新疆乌鲁木齐830054

出　　处：《心脏杂志》2007年第6期716-719,共4页Chinese Heart Journal

摘　　要：目的观察应用Amplatzer封堵器治疗继发孔房间隔缺损的术后远期疗效及安全性。方法应用Amplatzer封堵器治疗129例房间隔缺损(ASD)患者,于术后随访观察并发症的发生及心功能的改变,同时记录心脏超声、心电图及胸片结果。结果所有患者术后随访19～62(40±12)月。随访中所有Amplatzer封堵器位置准确、稳定,无装置变形及折断,无脱落、溶血等严重并发症。ASD患者术后左室收缩功能较术前显著改善[(1±10)%vs(73±11)%,P<0.05],直径大于20mm及缺损残余边缘≤4mm的ASD患者,术后心功能改善明显。心电图随访未见房颤、房扑及室性心律失常,92例原有右束支传导阻滞患者中,17例消失于术后6个月内,75例成为永久性。胸片随访示全部患者肺血减少、心胸比例不同程度缩小。结论Amplatzer封堵器治疗ASD改善了心功能,并发症少,远期疗效肯定。AIM To identify long term outcomes of the transactheter closure of the atrial septal defect with Amplatzer occluder. METHODS One hundred twenty-nine patients with the atrial septal defect were treated with Amplatzer occluder device through percutaneous procedure. The patients were assessed with echocardiography, twelve-lead electrocardiography and chest X-ray before and after transcatheter closure and during the long term follow-up. RESULTS All Amplatzer occluder were in good place, nicely and stably. No severe complication was found during the follow-up. The left ventricular systolic function increased significantly in all patients [ （61 ± 10） % vs （73 ± 11 ） % （ P 〈 0.05 ） ]. Electrocardiographic analysis showed that there was no atrial fibrillation, atrial flutter or ventricular arrhythmia. Among the 92 cases with RBBB, RBBB disappeared in 17 cases six months after operation and 75 cases still had it. CONCLUSION Transactheter closure of atrial septal defect with Amplatzer occluder increases ventricular systolic function and produces good clinical long-term outcomes.

关 键 词：房间隔缺损 心脏导管插入术 AMPLATZER封堵器 远期疗效 

分 类 号：R541.1[医药卫生—心血管疾病] R654.2[医药卫生—内科学]