急性心肌缺血时左心室压力变化影响左心房功能的应变率显像研究  

The effect of left ventricular pressure changing on left atrial function studied with strain rate imaging under acute left ventricular ischemia

作　　者：穆玉明[1] 陈晓峰[1] 唐琪[1] 王春梅[1] 关丽娜[1] 吐尔逊娜依·阿迪[1] 

机构地区：[1]新疆医科大学第一附属医院心脏超声诊断科,乌鲁木齐830000

出　　处：《中华超声影像学杂志》2007年第11期989-992,共4页Chinese Journal of Ultrasonography

基　　金：新疆维吾尔自治区自然科学基金项目（200421101）

摘　　要：目的应用超声应变率显像（SRI）技术研究犬左室局部心肌缺血时左室压力变化对左房功能的影响。方法11只犬行左冠状动脉前降支结扎形成左室前壁心肌缺血,应用SRI测量缺血前后左房各壁存储期（包括早期和晚期）、通道期和收缩期应变率及二尖瓣和肺静脉频谱相关指标,同时导管记录缺血前后左室压力曲线。结果心肌缺血后左房各壁各期峰值应变率（PSR）均增高（P〈0.001）,左室舒张末期压力增高且其缺血前后变化率分别与左房前壁和侧壁收缩期和通道期PSR变化率呈正相关（r=0.72,0.72,0.83,0.73;P=0.05,0.05,0.002,0.01）。结论左房功能在局部心肌缺血时会受到增高的左室舒张末期压力的影响,表现为左房壁形变能力随之增加。Objective To evaluate whether left atrial（LA）function will be affected by the left ventricular（LV）pressure changing during the LV ischemia using strain rate imaging（SRI）.Methods Eleven healthy dogs were occluded with left anterior descending coronary artery（LAD）for regional acute ischemia.Peak SR（PSR）value of LA walls during reservoir（including ER and LR）,conduit（CD）and contractile（CT）phases and catheter-measured pressure of LV were measured both at pre-and post-ischemia condition respectively.Results All PSR values increased after ischemia（P〈0.001）.Left ventricular end diastolic pressure（LVEDP）increased after ischemia（P〈0.001）and its changing rate（LVEDP%）positively correlated with the changing rate of CT-PSR and CD-PSR of anterior and lateral wall respectively（r=0.72,0.72,0.83,0.73;P=0.05,0.05,0.002,0.01）.Conclusions LA function will be partially affected by the LVEDP changing raised by regional LV ischemia.Presented as the compensated increased wall deformation after regional acute LV ischemia.

关 键 词：超声心动描记术 心肌缺血 心室功能 左 心房功能 左 应变率显像 

分 类 号：R686[医药卫生—骨科学]