腔内超声显象法对家兔动脉脂质斑块的在体量化  

Quantitative Assessment of Lipid Deposits in Arterial Walls by Intravascular Ultrasound Imaging in Rabbits

作　　者：顾振良[1] 方秀英[1] 蒋文平[1] 

机构地区：[1]苏州医学院附属第一医院心血管病研究室

出　　处：《上海实验动物科学》1997年第2期74-76,共3页Shanghai Laboratory Animal Science

摘　　要：对２０只动脉硬化的雄性新西兰兔作了血管腔内超声（ＩＶＵＳ）显象和病理学检查，测定脂质斑块的截面积、厚度以及病变血管管腔的截面积和直径。结果：实验家兔均有动脉脂质沉积的病理改变；超声显象示血管壁内面有突向腔内的低回声区，其面积为０．７１±０．２６ｍｍ２，厚度达０．２７±０．０９ｍｍ，与病理学检查所见斑块相符，提示用ＩＶＵＳ对脂质斑块作在体量化是切实可行的。To develop a new means of quantitating lipid deposits in vivo the authors performed intravascular ultrasound (IVUS) imaging on twenty atherosclerotic male New Zealand White rabbits, measured the sectional area and thickness of the plaques, the lumen area and diameter in lesion arteries. The results revealed that all of the rabbits were found with lipid deposits with the features of hypoechosic areas in IVUS image that adhered to the inner of the arterial walls and were coincided with the histopathologic observations. The sec tional area of the plaques was 0.71±0.26mm 2,and the thickness was 0.27±0.09mm. The authors consider that IVUS imaging would be a new means of quantitative assessment for the lipid deposits in vivo.

关 键 词：动脉硬化 血管腔内 超声显象 脂质斑块 在体量化 

分 类 号：R543.504[医药卫生—心血管疾病]