MR波谱脂峰对前列腺中央腺体谱线的影响  

Study on the influence of lipid peak to the results of MR spectroscopy in the centraI gland of prostate

作　　者：佟艳军[1] 王霄英[2] 李飞宇[2] 蒋学祥[2] 

机构地区：[1]北京大学航天中心医院放射科,100039 [2]北京大学第一医院放射科,100034

出　　处：《中华放射学杂志》2007年第12期1390-1393,共4页Chinese Journal of Radiology

摘　　要：目的探讨 MR 波谱(MRS)中脂峰对前列腺中央腺体谱线的影响。方法对17例因良性前列腺增生(BPH)行经尿道前列腺切除术(TURP)患者的 MRS 谱线作回顾性分析,根据病理结果分为3组:中央腺体偶发癌(IDPC)组4例、腺体增生为主的 BPH(glandular BPH,GBPH)组7例,基质增生为主的 BPH(stromal BPH,SBPH)组6例。统计中央腺体感兴趣区内出现脂峰的体素,并与病理结果对照,分析脂峰在中央腺体出现的常见位置及对 MRS 谱线识别产生的干扰。结果位于中央腺体的 MRS 体素共3567个,有脂峰体素834个,占中央腺体总体素的22.8%。其中,GBPH、SBPH 和IDPC 组测量的体素数分别为1477、1434和656个,有脂峰体素分别为397、396和41个。上述3组患者有脂峰体素所占比率的中位数分别为23.6%、27.2%和6.4%。有脂峰体素多位于中央腺体的边缘,3组所占比率的中位数分别为79.6%、68.6%和72.4%。脂峰多不会对谱线识别造成干扰,3组所占比率中位数分别为82.8%、98.0%和96.4%。结论前列腺中央腺体的 MRS 谱线中,脂峰可能与腺体周围脂肪组织有关,而且大多数未影响到谱线的识别。Objective To study the influence of lipid peak to MRS in central gland of prostate gland. Methods Seventeen patients performed transurethral resection of prostate （TURP） for benign prostate hyperplasia （BPH） were enrolled in this study. Three groups were divided according to the pathological findings ： glandular-BPH （ GBPH ） （ 7 cases ）, stromal-BPH （ SBPH ） （ 6 cases ）, and incidentally detected prostate carcinoma （IDPC） （4 cases）. The voxel with lipid peak in the field of volume was counted. Compared with pathology, the following studies were performed ： （ 1 ） The location of the voxels that more frequently presented lipid peak in the central gland. （2） Whether the appearance of the lipid peak would obscure the identification of the peaks of the endogenous metabolites. Results The ratio of voxels with lipid peak in central gland was about 22. 8% （ 834/3567 ）. There were 1477 （ 397 voxels with lipid peak） , 1434（396 voxels with lipid peak） , and 656（41 voxels with lipid peak） voxels in GBPH, SBPH, and IDPC groups, respectively. The percentage in GBPH, SBPH, and IDPC groups was 23.6% , 27.2% , and 6.4% , respectively. The percentage of voxels with lipid peak at the edge of the central gland （79.6% , 68.6% and 72.4% , respectively ） was higher than that in other regions. The lipid peak in most of the voxels didn＇t influence the identification of the citrate and choline peak （82. 8% , 98. 0%, and 96. 4%, respectively）. Conclusion The lipid peak in the central gland may result from the lipid tissues near the gland, and most lipid peak had no influence on the identification of endogenous metabolites.

关 键 词：前列腺增生 前列腺肿瘤 磁共振波谱学 

分 类 号：R445.2[医药卫生—影像医学与核医学]