低钾性周期性麻痹84例临床分析  

The clinical analysis of 84 patients with hypokalemic periodic paralysis

作　　者：苏亚碧 

机构地区：[1]云南省玉溪矿业医院,云南玉溪653100

出　　处：《中国医药导报》2007年第12Z期29-30,共2页China Medical Herald

摘　　要：目的:总结低钾性周期性麻痹(hypoKPP)的临床表现和疗效,探讨其发病机制及预防措施。方法:回顾分析84例确诊的低钾性周期性麻痹患者的临床资料。结果:84例患者中,原发性60例,其中有家族史者5例,散发54例;继发性24例,其中继发于甲亢者19例。有心电图资料者62例,其中,正常10例,有典型低血钾改变者52例。伴有四肢麻木者6例,肌肉酸痛者5例。经过口服和静脉注射钾后,全部病例均获得痊愈。结论:血清钾及心电图的检查有利于早期诊断及治疗。继发性者要加强原发病治疗,避免各种诱因是防止复发的关键。Objective：To explore the pathogenesy and the precaution of the hypokalemic periodic paralysis by summarizing the clinical situation and therapeutic effect. Methods：The clinical data of 84 patients with hypokalemic periodic paralysis were retrospectively analyzed.Results：There were 60 primarily patients,5 of them had family history,54 of them were diverging.There were 24 patients sequented by other diseases. 19 patients were followed by the hyperthyreosis.62 patients had ECG data,10 of them were nomal and 52 of them were typical hypokalemic.6 patients combined limbs anesthesia, 5 patients combined muscle acid. All patients were cured by taking potassium orally and intravenous injection.Conclusion：The primarily hypoKPP is a autosomal dominant inheritanced ion channel disease. Thyrotoxic Periodic Paralys is most common within the sequented hypoKPP.The test of serum potassium and the ECG are benefit to the early diagnosis and therapy of hypoKPP.The sequented patients should cure the primary diease,It＇s a key to prevent recrudescent to avoid all kinds of motivation.

关 键 词：低钾性麻痹 离子通道 骨骼肌瘫痪 

分 类 号：R591[医药卫生—内科学]