中国延边朝鲜族和延边汉族apoB,D17S30 VNTR多态性研究  

A Study on the Genetic Polymorphism of apoB,D17S30 Locus of Korean-Chinese and Han Nationality in Yanbian

作　　者：全贵红[1] 金东洙[1] 

机构地区：[1]延边大学医学院人体解剖学教研室,延吉133000

出　　处：《人类学学报》2007年第4期318-324,共7页Acta Anthropologica Sinica

摘　　要：应用聚合酶链反应(PCR)法对中国延边朝鲜族和延边汉族apoB和D17S30 VNTR研究发现,中国延边朝鲜族和延边汉族等位基因频率总体分布具有显著性差异(P<0.05);apoB和D17S30位点VNTR在中国延边朝鲜族和延边汉族中的观察杂合性、多态信息含量、个体鉴别力均大于0.7;中国延边朝鲜族和延边汉族中D17S30 VNTR位点分别以A3和A1的频率为最高。结果表明,apoB和D17S30 VNTR位点在中国延边朝鲜族和延边汉族中的等位基因频率分布具有很强的多态性,在研究中国延边朝鲜族起源、变迁以及与其他各民族间亲缘关系等方面具有广泛的应用价值,适用于中国延边朝鲜族和延边汉族的个体识别和亲子鉴定。The apoB and D17S30 locus, which has a high degree of polymorphism, is an important identifier that measures the value of genetic marker systems in the study of anthropology. Using polymerase chain reaction （PCR） technique, the variable number of tandem repeats （VNTR） of the apoB and D17S30 locus were studied in Korean-Chinese and people of the Han nationality of Yanbian.There was a significant difference（ P 〈 0.05） in the total distribution of allele frequencies of the apoB and D17S30 locus between these two groups. Heterozygosity, polymorphism information content and individual identification of the apoB and D17S30 were all greater than 0.7. These results indicate that： 1） the distribution of allele frequencies of apoB and D17S30 locus has the better degree of polymorphism in Korean-Chinese and Han nationality of Yanbian; 2 ） these loci are suitable for individual identification and paternity diagnosis; 3） this type of research is valuable for studying the origin of nationality, transition, national distinction and genetic relationships between nationalities.

关 键 词：载脂蛋白B D17S30位点 等位基因 聚合酶链反应 

分 类 号：Q987[生物学—遗传学]