纳洛酮联合生脉注射液治疗急性酒精中毒疗效观察  

CONTROLLED STUDY OF NALOXONE-SHENG MAI INJECTION IN TREATMENT OF ACUTE ALCOHOL POISONING

作　　者：郑文军[1] 刘江华[1] 雷卓青[1] 赵春菱[1] 林莉[1] 刘唐威[2] 

机构地区：[1]广西医科大学第一附属医院西院急诊科,南宁530007 [2]广西医科大学第一附属医院心血管研究所,南宁530007

出　　处：《广西医科大学学报》2007年第5期678-679,共2页Journal of Guangxi Medical University

基　　金：广西科学基金资助项目(科桂基0342009-5)

摘　　要：目的:观察纳洛酮联合生脉注射液治疗急性酒精中毒疗效。方法:65例急性酒精中毒患者随机分为治疗组34例和对照组31例。对照组给予纳洛酮治疗;治疗组给予纳洛酮和生脉注射液治疗。比较两组的临床疗效和兴奋及共济失调症状消失时间、心律失常持续时间、神志清醒时间。结果:①两组治愈率无明显差异(P>0.05)。②两组轻中度中毒者兴奋及共济失调症状消失时间比较无明显差异(P>0.05)。③两组重度中毒者比较,治疗组心律失常持续时间短于对照组,治疗组神志清醒时间短于对照组(P<0.05)。结论:纳洛酮联合生脉注射液治疗急性酒精中毒,对重度酒精中毒者可明显缩短心律失常持续时间和神志清醒时间,加快重度酒精中毒病人恢复。Objective：To observe the effect of Naloxone united Sheng Mai injection m treatment of acute alcohol poisoning. Methods：65 cases of acute alcohol poisoning patients were randomly divided into treated and control groups. The control group received Naloxone therapy, while the treated group was given Naloxone-Sheng Mai injection, then to compare the different therapy effect and the time of abnormal cardiac rhythm persisting,excited and mutual aid imbalance and consciousness awaking. Result： （1）efficacy rate of two groups had no significant difference（ P〉0.05）. （2）the time of excited and mutual aid imbalance had no significant difference between the two groups of mild and middle patients（ P〉0.05）. （3）the time of abnormal cardiac rhythm persisting and consciousness awaking for severe patients in treated groups was short than that in control group（ P〈0. 05）. Conclusion： Naloxone-Sheng Mai injection in treatment of acute alcohol poisoning shortened the time of abnormal cardiac rhythm persisting and the time of consciousness awaking for severe patients, which helps severe patients recover quickly.

关 键 词：纳洛酮 生脉注射液 急性酒精中毒 

分 类 号：R595.6[医药卫生—内科学]