The preparation of functionalized single walled carbon nanotubes as high efficiency DNA carriers  

作　　者：Xiao Ying Yang Zun Feng Liu Jie Mao Shu Jing Wang Yan FengMa Yong Sheng Chen 

机构地区：[1]School of Pharmaceutical Sciences, Tianjin Medical University, Tianjin 300070, China [2]Center for Nanoscale Science and Technology and Key Laboratory for Functional Polymer Materials, Institute of Polymer Chemistry, Nankai University, Tianjin 300071, China

出　　处：《Chinese Chemical Letters》2007年第12期1551-1553,共3页中国化学快报（英文版）

摘　　要：The positively charged single walled carbon nanotubes （SWNTs^＋） were prepared by conjugating with -CONH-C6H12-NH3^＋. The double strand DNA （dsDNA） chains were loaded onto SWNTs^＋ via the electrostatic interactions. SWNTs^＋ shows improved loading efficiency （353.5 μg/mg） toward dsDNA compared with that of charged free single walled carbon nanotubes （SWNTs） （82.9 μg/mg）.The positively charged single walled carbon nanotubes （SWNTs^＋） were prepared by conjugating with -CONH-C6H12-NH3^＋. The double strand DNA （dsDNA） chains were loaded onto SWNTs^＋ via the electrostatic interactions. SWNTs^＋ shows improved loading efficiency （353.5 μg/mg） toward dsDNA compared with that of charged free single walled carbon nanotubes （SWNTs） （82.9 μg/mg）.

关 键 词：Single wailed carbon nanotubes DNA Carder 

分 类 号：TQ0[化学工程]