检测头部血压和动态过程的头高位倾斜实验系统设计  

Design of a Head-up Tilt Experimental System for Measuring Head Blood Pressure and Its Dynamic Process.

作　　者：刘延勇[1] 俞梦孙[2] 向海燕[2] 姬军[3] 李音华[2] 秦瑜斐[2] 

机构地区：[1]第四军医大学生物医学工程系,陕西西安710032 [2]空军航空医学研究所,北京100036 [3]解放军305医院,北京100017

出　　处：《航天医学与医学工程》2007年第6期422-426,共5页Space Medicine & Medical Engineering

基　　金：国家"十五"科技攻关计划资助(2004BA706B15)

摘　　要：目的设计一个可以检测头部血压和动态过程的头高位倾斜实验(head-up tilt,HUT)系统,以提高HUT实验的效能。方法通过对阻抗血流图的B点和颞浅动脉脉搏波起点为标志点得到的脉搏波传导时间(pulse wave transit time,PWTT)进行个体化校正,获得头部血压。基于改进的倾斜床,设计了可监测连续动态血压、心电图、心音、呼吸和阻抗血流图等人体生理信号的实验系统;并通过3名志愿者的HUT实验检验系统的可靠性。结果基于精确的PWTT的个体化校正可以实现头部血压测量。在HUT过程中系统可连续、稳定地记录各项生理指标;可特征地显示出头部血压的最低值和血压的动态调节过程及整体水平。结论本系统可准确地反映HUT中头部血压的连续、动态变化过程,从而为评价人体的心血管调节功能提供更丰富的信息,为研究高性能飞机飞行员对加速度应激的即刻反应提供了可能。Objective To design a head-up tilt （HUT） experimental system which is capable of measuring head blood pressure and its dynamic process, to enhance the efficiency of HUT experiment. Methods The head blood pressure was calculated by the individual-calibrated pulse wave transit time （PWTT） measured from the B point of the ICG to the beginning point of the superficial temporal artery pulse wave. Based on the improved tilt bed, the HUT experimental system was designed to detect the dynamic blood pressure, ECG, PCG, respiration and ICG continuously. Finally, the system performance was examined by HUT experiments of three volunteers. Results Head blood pressure was calibratd with individual precise PWTT. The system detected physiological signals continu- ously and stablyduring HUT experiments; and our preliminary results presented the minimum value, dynamic regulating process and overall level of head blood pressure. Conclusion The system can exactly describe continuous, dynamic and transient process of head blood pressure during HUT ex- periments, which will provide more information about the regulation function of cardiovascular system. It is possible to study the instant responses of pilot to ＋ Gz stresses in high-perfomance aircraft.

关 键 词：头高位倾斜 头部血压 动态过程 脉搏波传导时间 个体化校正 

分 类 号：R318.6[医药卫生—生物医学工程] R852.2[医药卫生—基础医学]