2006年山西省运城市艾滋病患者免费抗病毒治疗断面疗效评估  

The 2006 cross-sectional outcome evaluation of charge-free antiviral therapy for AIDS in rural areas in southern Shanxi

作　　者：周仁义[1] 陆立星 王晋生[1] 曲淑霞[1] 李秀兰[1] 孙燕[1] 

机构地区：[1]山西省运城市疾病预防控制中心艾滋病防治科,044000

出　　处：《中国药物与临床》2007年第12期908-910,共3页Chinese Remedies & Clinics

基　　金：山西省第三轮全球基金课题资助项目

摘　　要：目的评价免费抗病毒药物对山西省运城市艾滋病(AIDS)患者的疗效。方法设计疗效调查表,对运城市截止到2006年2月接受免费抗病毒治疗的185例AIDS患者进行断面调查。包括:服药情况、机会性感染、体重、白细胞、血红蛋白、CD4+T检测以及精神、饮食、睡眠、生产劳动等情况。结果抗病毒治疗的AIDS患者服药依从性、机会性感染处置情况较好,治疗前后CD4+T均值由110.43个/μl上升到239.04个/μl(P<0.01),精神、饮食、睡眠、生产劳动情况也有明显改善(P<0.01)。结论免费抗病毒药物对艾滋病患者治疗效果显著,延长了生命,极大地改善了AIDS患者的生存质量,降低了机会性感染,CD4+T计数值显著提高。Objective To evaluate the outcome of charge-free antiviral therapy for AIDS in Yuncheng City,southern Shanxi.Methods A cross-sectional survey was conducted in 185 patients with AIDS who were on a charge-free antiviral therapy as of February 2006 in Yuncheng City,using a designated curative-effect questionnaire.The data investigated included use of antivirals,opportenistic infections,body weight,leukocyte,hemoglobin,CD4^＋T assay,mental status,diet,slecping and working.Results Good compliance and opportunistic infection control were seen in AIDS patient who were on antiviral therapy.After treatment,mean CD4^＋T count increased from 110.43 ceus/μl to 239.04ceus/μl（P〈0.01）.Scores of mental status,diet,sleeping and working were also notably improved （P〈0.01）.Conclusion The charge-free antiviral medication proved remarkable outcomes amony AIDS patients with extended life-time,greatly improved quality of life,reduced opportunistic infections and significantly elevated CD4^＋T counts.

关 键 词：农村卫生 获得性免疫缺陷综合征 抗病毒药 治疗结果 

分 类 号：R512.91[医药卫生—内科学]