肥胖与结直肠肿瘤发生的机制研究  

Study on Mechanism of Obesity and Development of Colorectal Cancer

作　　者：王娜[1] 黄志刚[1] 陈锡美[1] 

机构地区：[1]同济大学附属同济医院消化内科,200065

出　　处：《胃肠病学》2007年第11期701-703,共3页Chinese Journal of Gastroenterology

摘　　要：超重或肥胖是一种病理状态,近年研究认为肥胖是包括结直肠癌在内的多种肿瘤的危险因素之一。目前研究发现脂肪组织分泌的一些因子与结直肠肿瘤发生、发展相关。本文针对肥胖的病理生理状态以及相关因子与结直肠肿瘤发生的分子机制作一综述。Overweight or obesity is a pathologic status. Recently, obesity is known as one of the risk factors of several kinds of tumors including colorectal cancer. Some studies showed that fat tissue could secrete some factors relevant to the development and progress of colorectal cancer. This review article introduced the pathophysiological status of obesity and the correlation between relevant factors and the molecular mechanism of colorectal cancer.

关 键 词：肥胖症 结直肠肿瘤 分子作用机制 

分 类 号：R589.2[医药卫生—内分泌] R735.3[医药卫生—内科学]