术中应用透明质酸对腹腔镜治疗不孕症妊娠结局的影响  

The effect of hyaluronic acid on the pregnancy outcome of infertile patients who underwent laparoscopic treatment

作　　者：李艳[1] 杜江平[2] 王霞[3] 柯小宁[1] 

机构地区：[1]河北峰峰集团公司总医院邯郸医院,056002 [2]河北工程大学临床医学院 [3]河北省邯郸市妇幼保健院

出　　处：《中国妇幼保健》2007年第34期4895-4896,共2页Maternal and Child Health Care of China

摘　　要：目的:观察腹腔镜治疗不孕症时用透明质酸对妊娠结局的影响`。方法:72例患者随机分为两组。研究组32例在术中使用透明质酸局部涂并注入输卵管;对照组40例为空白对照。术后随访6个月,观察两组病例输卵管通畅情况与受孕率。结果:研究组失访0例,对照组1例。妊娠者研究组为18例,对照组8例。未孕者行输卵管造影示研究组2条阻塞,对照组18条。两组在自然妊娠率与输卵管阻塞率均有显著差异(P<0.05)。结论:在腹腔镜治疗不孕症时,透明质酸术中应用,防粘连效果理想,能够提高妊娠率。Objective： To observe the effect of hyaluronic acid on the pregnancy outcome of infertile patients who underwent laparoscopic treatment. Methods： 72 cases were divided into two groups. 32cases of therapeutic group accepted hyalurunic acid during laparoscopic treatment. 40 eases of control group underwent only laparascopic treatment. All patients were followed up after 6 months. Their pregnancy rate and the unobstructed condition of fallopian tube were analyzed. Results One cases lost follow - up in control group. 18 cases in therapeutic group were pregnancy, and 8 cases in control group. The obstructed condition of fallopian tube of after the surgery unfertilized patients were 2 oviducts in therapeutic group and 18 oviducts in control group. Those parameters were significant （P 〈 0. 05 ） during treatment. Conclusion： Hyaluronic acid is a promising barrier for the reduction of postoperative adhesion after laparoscopic treatment in unfertilized patients. Moreover, pregnancy rate is significantly higer with the use of hyaluronic acid during laparoscopic treatment.

关 键 词：防粘连剂 腔镜 手术 不孕症 妊娠结局 

分 类 号：R711.6[医药卫生—妇产科学]