109例支气管-肺念珠菌感染的临床分析  

Clinical Analysis of 109 Patients with Candida Infection in Bronchi-lung

作　　者：娄源杰[1] 王同生[1] 毛毅敏[1] 潘丽娟[1] 张英民[1] 

机构地区：[1]河南科技大学第一附属医院呼吸内科,河南洛阳471003

出　　处：《中国现代医生》2007年第11S期14-15,共2页China Modern Doctor

摘　　要：目的探讨支气管-肺念珠菌感染的危险因素及预防措施。方法回顾分析我院2001年1月～2006年12月送检念珠菌阳性109例患者,分析念珠菌感染的病因、临床表现及治疗。结果109例患者白色念珠菌感染率最高,为56.88℅(62/109),其次为热带念珠菌14.68℅(16/109)、克柔念珠菌11.01℅(12/109)、光滑念珠菌11.01℅(12/109)。死亡率13.76℅。结论长期广谱抗生素使用、细胞毒性药物、免疫抑制是继发念珠菌感染的重要原因。早期预防,早期诊断,及时治疗,选择合适的抗念珠菌药物,提高免疫力及支持治疗,才能取得比较满意的疗效。Objective To investigate the risk factors and preventive methods of candida infection in bronchi-lung. Methods The clinical materials of 109 patients infected with candida from January 2001 to December 2006 were retrospectively analyzed about the etiological factor, diagnosis and treatment. Results The infection rate of candida albicans was as high as 56.88%（62/109）, that of tropicalis, krusei and glabrata covered 14.68%（16/109）, 11.01%（12/109）, and 11.01%（12/109） respectively. The mortality rate was 13.76%. Conclusion The important reasons for the secondary candida infection in bronchi-lung are long-term application of broad-spectrum antibiotic usage or cytotoxic agent and the degression of immunity in patients. In order to get a satisfactory curative effect, early precaution and diagnosis, prompt treatment, select the suitable antifungal agent and improve the immunity and nutrition of patients should been done for the patients accompanied with candida infection of bronchi-lung.

关 键 词：支气管-肺感染 念珠菌 诊断 治疗 

分 类 号：R563.1[医药卫生—呼吸系统]