恶性肿瘤患者嗜酸性粒细胞增多性浆膜腔积液分析  

Cytological analysis of malignant serous cavity effusion with eosinophilia

作　　者：周道银[1] 许晓峰[2] 王学[1] 俞靖龙[1] 张力[1] 

机构地区：[1]上海第二军医大学附属长海医院实验诊断科,上海200433 [2]上海市华东医院市府大厦门诊部,上海200002

出　　处：《检验医学》2007年第6期660-663,共4页Laboratory Medicine

摘　　要：目的对恶性肿瘤患者嗜酸性粒细胞增多性浆膜腔积液进行分析,探讨嗜酸性粒细胞增多与恶性肿瘤的关系,为临床诊断治疗提供参考。方法浆膜腔积液常规检查的制片采用推片法,以改良的瑞吉复合染色法鉴定细胞。结果40例恶性肿瘤患者嗜酸性粒细胞增多性浆膜腔积液细胞涂片分类嗜酸性粒细胞相对数为10%-86%,均值为28.2%。查见恶性细胞24例,未查见恶性细胞16例。28例已确认远处转移。结论恶性肿瘤患者浆膜腔积液中出现嗜酸性粒细胞增多可能提示疾病的恶化和愈后不良;恶性肿瘤患者的浆膜腔积液嗜酸性粒细胞增多与血液嗜酸性粒细胞不一定平行。Objective To analyze the cytology of malignant serous cavity effusion with eosinophilia and study the eosinophiliosis mechanism and the relationship with malignant cancer for providing reference to elinical therapy and diagnosis. Methods The smearing method was adopted in the cavity effusion routine, and cells were identified by Wright- Giemsa staining. Results 40 effusion samples with eosinophi]ia from cancer patients were involved in this study. The relative number of eosinocyte was 10% -80% and the mean was 28.2%. Malignant cells were found in 24 samples and not in 16 samples. 28 eases were identified metabasis. Conclusions Our results might suggest unfavourable prognosis that eosinophilia was found in effusion from cancer patients, There might not be a parallel relationship between the eosinophilia in effusion and that in blood.

关 键 词：浆膜腔积液 嗜酸性粒细胞增多 肿瘤细胞 

分 类 号：R557.3[医药卫生—血液循环系统疾病]