以药对拆方研究小柴胡汤对小鼠小肠推进作用的影响  

Promoting Effect of Separated Paired Drugs in Xiaochaihu Decoction on the Small Intestine of Mice

作　　者：李连珍[1] 吴磊[2] 王宪龄[2] 

机构地区：[1]河南农业大学,河南郑州450000 [2]河南中医学院,河南郑州450008

出　　处：《河南中医》2007年第12期28-30,共3页Henan Traditional Chinese Medicine

基　　金：河南省自然科学基金课题(编号:994021900);河南省重大科技攻关项目(编号:0522030302)

摘　　要：目的:研究小柴胡汤以不同药对拆方对小鼠小肠推进作用的影响。方法:把小柴胡汤中的药物按功能分为柴胡与黄芩组,人参、甘草与大枣组,半夏与生姜组,然后按正交实验法设计,以炭末推进的百分率为指标进行测定。结果:半夏与生姜组对小鼠小肠推进作用较明显;人参、甘草与大枣三药组成的补益药对表现出抑制作用;对柴胡黄芩组设了四个不同水平进行研究,由方差分析的结果可知,二者以1∶1的比例配伍作用较好。结论:半夏与生姜组能显著促进小肠的推进功能,而柴胡与黄芩组次之。Objective： To study the promoting effect of separated paired drugs in Xiaochaihu Decoction on the small intestine of mice. Methods： The components of Xiaochaihu Decoction were divided into Banxia Shengiiang group, Jinseng Gancao and Dazao group and Chaihu Huangqin group according to their functions. Then they were detected on the basis of the orthogonal test method and the percentage index promoted by carbon powder. Results： Banxia Shengjiang group had a remarkable promoting effect, and the reinforcement drugs made by Ginsheng, Gancao and Dazao expressed a resistant effect. The study of Chaihu Huangqin group was established in 4 different levels, and the proportion of one to one between Huangqin and Chaihu would be better according to the results from analysis of variance. Conclusion： Banxia Shengjiang Group can apparently enhance the promoting function of the small intestine, while Chaihu Huangqin group takes the second place.

关 键 词：小柴胡汤 药对 正交设计法 小肠 小鼠 

分 类 号：R285.5[医药卫生—中药学]