双氯芬酸钠栓与对乙酰氨基酚栓治疗小儿急性发热对比分析  

Clinical effect comparison between diclofenac sodium suppository and paracetamol suppository in curing acute fever of children

作　　者：郑军[1] 

机构地区：[1]武汉大学医学院武汉市妇女儿童医疗保健中心,湖北武汉430016

出　　处：《儿科药学杂志》2007年第6期21-23,共3页Journal of Pediatric Pharmacy

摘　　要：目的:探讨双氯芬酸钠栓剂和对乙酰氨基酚栓在儿科临床的退热效果和安全性,为临床选择退热药提供参考。方法:100例急性发热患儿随机分为观察组和对照组,观察组予双氯芬酸钠栓0.5 mg/(kg.次),肛门给药;对照组予对乙酰氨基酚栓10mg/(kg.次),肛门给药。结果:观察组的起效时间[(41.63±3.71)min]短于对照组[(55.19±5.11)min],维持正常体温的时间[(7.31±1.62)h]长于对照组[(6.57±1.73)h],两组比较差异均有统计学意义(P<0.01)。结论:双氯芬酸钠栓对高热患儿具有退热作用快,维持时间长,使用方便、安全,无明显胃肠道反应等特点。Objective： To study the effect and security of diclofenac sodium suppository and paracetamol suppository in febrifie children, and suggest febrifuge in clinic practice. Methods： 100 infected children were randomly divided into two groups. The observation group was used with diclofenac sodium suppository to insert into anus, 0.5 mg/kg each time, The control group was used paraeetamol suppository to insert into anus, 10 mg/kg each time. Results： The time needed for observation group to reduce fever [ （41.63 ± 3.71 ）mini was shorter than the time of control group [ （55.19 ± 5.11 ） rain ], and the time for observation group [ （7.31 ± 1.62） h ] to maintain normal temperature was longer than the time ot control group [ （6.57 ± 1.73）h]. There were statistically differences between the observation group and the control group （ P 〈 0.01 ）. Conclusions： To children suffering from soaring temperature, diclofenac sodium suppository has the characteristics of bringing down fever promptly, maintaining time long, and easy to use, safe, no obvious gastrointestional symptoms.

关 键 词：双氯芬酸钠栓剂 对乙酰氨基酚栓 发热 儿童 

分 类 号：R971.1[医药卫生—药品]