更昔洛韦治疗咽-结合膜热疗效观察  

Observation of the curative effect of ganciclovir on pharyngo-conjunctival fever

作　　者：王春燕[1] 

机构地区：[1]浙江省义乌市中心医院,浙江义乌322000

出　　处：《儿科药学杂志》2007年第6期48-49,共2页Journal of Pediatric Pharmacy

摘　　要：目的:探讨更昔洛韦治疗小儿咽-结合膜热疗效。方法:将150例咽-结合膜热患儿随机分为观察组和对照组,分别给予更昔洛韦及利巴韦林治疗,观察两组发热持续时间、咽-结合膜炎持续天数及药物的不良反应。结果:观察组平均发热时间(2.76±1.06)d,咽-结合膜炎持续时间(3.95±1.69)d,明显短于对照组的(4.25±1.58)d和(5.21±1.32)d(t=2.37、2.65,P均<0.01)。观察组总有效率82.7%,对照组总有效率34.7%,两组比较差异有统计学意义(χ2=36.57,P<0.01)。两组不良反应轻微。结论:更昔洛韦治疗咽-结合膜热较利巴韦林更有效。Objective： To investigate the curative effect of ganciclovir on pharyngo-conjunctival fever. Methods： 150 children with pharyngo- conjunctival fever were divided into two groups. The observation group treated with ganciclovir and the control group treated with virazole. The durations of fever and of conjunctivitis of the two groups were compared, and the side effects of the two drugs were observed. Results： The duration of fever in observation group was significantly shorter than that of control group （ P 〈 0.01 ） ; the duration of conjunctivitis in observation group was also shorter than that of the control group （P 〈 0.01）. The adverse reactions of two groups were relatively minor. Conclusions： ganciclovir is more effective than virazole on pharyngo-conjunctival fever.

关 键 词：更昔洛韦 腺病毒 咽-结合膜热 儿童 

分 类 号：R978.7[医药卫生—药品]