心肌酶谱在急性毒鼠强中毒病程中的变化及意义  

Relationship between the changes of spectrum of myocardial enzymes and significance during the course of disease follwed by acute poisoning of tetramine

作　　者：单智勇[1] 

机构地区：[1]河南省商丘市第一人民医院急诊科,商丘476100

出　　处：《中原医刊》2007年第23期27-28,共2页Central Plains Medical Journal

摘　　要：目的探讨急性毒鼠强中毒时心肌酶谱的变化与临床的关系。方法将47例急行毒鼠强中毒患者分为伴抽搐组和非抽搐组分别在入院即刻，12h、24h、48h、96h采血化验心肌酶谱和作床边心电图。结果伴抽搐组肌酸磷酸激酶（CPK）、肌酸磷酸激酶同工酶（CK—MB）、乳酸脱氢酶（LDH）、α-羟丁酸酶（α—HBD）均明显增高，丙氨酸氨基转移酶（ALT）、天门冬氨酸氨基转移酶（AST）增高不明显；非抽搐组，心肌酶谱各项增高均不明显。两组异常心电图的发生率均较低。结论急性毒鼠强中毒患者心肌酶谱的改变主要是由于抽搐引起，而与心肌损伤的相关性较低。Objective To investigate the relationship between the changes of the spectrum of myocardial enzymes followed by acute poisoning of tetramine. Methods Forty - seven patients were divided into convulsive group and non - convulsive group. Tested the spectrum of myocardial enzymes and bedside ECG at the time points of 12 h ,24 h,48 h,96 h. Results Compaired with non -convulsive group, CPK, CK- MB, LDH and α - HBD were significantly higher than that in convulsive group. ALT,AST were not high enough, non -convulsive group, there was no significantly higher in the spectrum of myocardial enzymes. Both groups had low rate of abnormal ECG occurance. Conclusion The changes of spectrum of myocardial enzymes in the patients of acute teramine poisoning were caused by convulsion ,have low relationship with the injury of myocardial.

关 键 词：心肌酶谱 毒鼠强 中毒 

分 类 号：R5[医药卫生—内科学]