HPLC法测定苦参素注射液中氧化苦参碱的含量  

Content Deternination of Oxymatrine in Marine Injection by HPLC

作　　者：孟祥超[1] 马琳[2] 

机构地区：[1]广东岭南职业技术学院,广东广州510663 [2]广州白云山和记黄埔中药有限公司,广东广州510515

出　　处：《国际医药卫生导报》2007年第24期53-55,共3页International Medicine and Health Guidance News

摘　　要：目的建立苦参素注射液的含量测定方法。方法以氧化苦参碱，氧化槐果碱为对照品，采用高效液相色谱法进行含量测定。结果氧化苦参碱在0．604～1．412μg范围内呈良好线性关系，r=0．9997，n=6。平均加样回收率为99．7％，RSD=0．26％，阴性对照无干扰。结论该方法结果准确，重复性好，可以作为苦参素注射液的质量控制方法。Objective To establish the method for Marine Injection. Methods The Oxymatrine and Oxysophocarprine were detrnined by HPLC. Results The average recovery of Oxymatrine was 100%,and RSD was 0. 078%,respectively. Conclusions The method developed is accurate and the reproducibility is good. The method can be used for quality control of the Marine Injection.

关 键 词：苦参素注射液氧 化苦参碱 氧化槐果碱 HPLC 

分 类 号：O65[理学—分析化学] R28[理学—化学]