2型糖尿病患者听力损害的相关性分析  

Risk factors of hearing impairments in type 2 diabetic patients

作　　者：崔小康[1] 任建民[1] 许安廷[2] 肖晓燕[1] 樊云霞[1] 孙磊[1] 

机构地区：[1]山东大学齐鲁医院内分泌科,济南250012 [2]山东大学齐鲁医院耳鼻喉科,济南250012

出　　处：《山东大学学报（医学版）》2007年第11期1144-1147,共4页Journal of Shandong University:Health Sciences

摘　　要：目的探讨糖尿病合并听力损害患者纯音测听(PTA)、脑干听觉诱发电位(ABR)和畸变产物诱发电位(DPOAE)改变的特点。方法测定134例2型糖尿病患者的纯音测听、脑干听觉诱发电位和畸变产物诱发电位结果,回顾性分析听力正常组和异常组的临床资料,并应用多因素logistic回归分析探讨影响听力的危险因素。结果41.8%的2型糖尿病患者出现听力学改变,听力正常组与异常改变组之间的年龄、病程、LDL-C、GHbA1c水平差异有统计学意义(P<0.05);Logistic回归分析显示,年龄、病程、LDL-C及视网膜病变为糖尿病听力损害的危险性因素。结论2型糖尿病患者听力损伤的比例较高且临床症状不明显,门诊的积极听力学检查有助于糖尿病听力损害的早期诊断和干预治疗。Objective To study the characteristics of hearing impairments in type 2 diabetic patients. Methods 134 patients with type 2 diabetes were determined by pure tone audiometry（P-FA）, auditory brainstem response（ABR） and distortion product otoacoustic emissions （DPOAE）. The risk factors of hearing loss were analyzed by logistic regression analysis. Results 41.8% patients had hearing loss. There were significant differences in age, duration of the T2DM, LDL-C and GHbAlc between the normal and the abnormal groups（ P 〈 0.05）. kogistic regression analysis sug- gested that age, duration of the T2DM, LDL-C and DR were independent risk factors of hearing impairments in type 2 di- abetic patients. Conclusions There are many type 2 diabetic patients with sub-clinical hearing loss. Active hearing tests are helpful in early diagnosis and treatment.

关 键 词：糖尿病 非胰岛素依赖型 聋 测听法 纯音 诱发电位 危险因素 

分 类 号：R587.2[医药卫生—内分泌]