乙腈溶液中亚硝酸苄(醇)酯系列化合物NO化学亲和势的测定  

Determination of NO Chemical Affinities of Benzyl Nitrite in Acetonitrile

作　　者：李鑫[1] 朱晓晴[1] 程津培[1] 

机构地区：[1]南开大学元素有机化学国家重点实验室化学系,天津300071

出　　处：《高等学校化学学报》2007年第12期2327-2329,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:20332020和20472038)资助

摘　　要：There is an increasing interest for the study of NO affinity of organic nitrite,for the biological and physiological effects of organic nitrites seem to be due to their ability releasing NO.In this paper,NO chemical affinities of ten benzyl nitrites were determined respectively by titration calorimetry and from a thermodynamic cycle in acetonitrile solution.The results show that ΔHhet of O—NO in the O-nitroso compounds were substantially larger than the corresponding ΔHhomo of O—NO in the same compounds,suggesting that these O-nitroso compounds were much easier release NO radical by the O—NO bond homolytic cleavage.It is believed that the structural and energetic information disclosed in this work should be useful in understanding chemical and biological functions of organic nitrites.There is an increasing interest for the study of NO affinity of organic nitrite, for the biological and physiological effects of organic nitrites seem to be due to their ability releasing NO. In this paper, NO chemical affinities of ten benzyl nitrites were determined respectively by titration calorimetry and from a thermody- namic cycle in acetonitrile solution. The results show that AHhe, of O—NO in the O-nitroso compounds were substantially larger than the corresponding AHh of O--NO in the same compounds, suggesting that these O-nitroso compounds were much easier release NO radical by the O--NO bond homolytic cleavage. It is believed that the structural and energetic information disclosed in this work should be useful in understanding chemical and biological functions of organic nitrites.

关 键 词：亚硝酸苄(醇)酯 化学亲和势 O—NO键能 滴定量热 

分 类 号：O621.1[理学—有机化学]