益肺抗瘤饮对肺癌转移及免疫功能的影响  被引量:74

Effect of Yifei Kangliu Yin on Lung Cancer Metastasis and Immune Function

在线阅读下载全文

作  者:许玲[1] 刘嘉湘[1] 

机构地区:[1]上海长征医院,上海龙华医院

出  处:《中国中西医结合杂志》1997年第7期401-403,共3页Chinese Journal of Integrated Traditional and Western Medicine

基  金:上海市高教局资助

摘  要:目的:探讨益肺抗瘤饮对肺癌转移的抑制作用及其对免疫功能的影响。方法:(1)观察3组(94例)肺癌患者远处转移灶,用放射免疫测定法测定患者的NK细胞。OKT3、OKT4、OKT8值,并分组比较分析;(2)运用C57小鼠B16黑色素瘤模型观察益肺抗瘤饮对肺转移灶数的影响,并用免疫组织化学法观察转移灶周围T4、T8淋巴细胞的改变。结果:益肺抗瘤饮具有降低肺癌患者远处转移和减少B16黑色素瘤肺转移的作用,而且益肺抗瘤饮能提高患者外周血NK细胞活性及OKT3、OKT4值,增加B16黑色素瘤肺转移灶周围T4淋巴细胞的浸润。结论:益肺抗瘤位可能是增强了机体的免疫功能,调动患者自身的抗肿瘤能力,从而阻止癌转移的发生。Objective:To explore the effect of Yifei Kangliu Yin (YFKLY) on metastasis of lung cancer and immune function. Methods: (1) Observing remote metastasis of three groups (n = 94) lung cancer patients, measuring the activity of NK cell, and the levels Of OKT3, OKT4 of the patients by radioimmunoassay, and duing compared analysis. (2) Observing the effect of YFKLY on C57 mice B16 melanoma, and examining T4, T8 around the foci of cancer metastasis by immunohistochemical method. Results: YFKLY significantly reduced the incidence of remote metastasis in patients and reduced the metastasis fool numbers on C57 mice of B16 melanoma. It was found that NK cell activities, OKT3 and OKT4 in peripheral blood of patients significantly increased, the infiltration of T4 lymphocytes around the fool of cancer metastasis also increased. Conclusion: YFKLY had inhibitory effect on the metastasis of cancer cells. It had strengthened the immune functions, aroused the anti-tumor capability.

关 键 词:益肺抗瘤饮 转移 肺肿瘤 中医药疗法 

分 类 号:R273.420.5[医药卫生—中西医结合]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象