中药穴位注射治疗勃起功能障碍随机对照研究  

Randomized and controlled research of Chinese drug acupoint injection therapy for erectile dysfunction

作　　者：崔云[1] 冯奕[1] 陈雷[1] 周毅[2] 杨燮樵[3] 贺娟[1] 孙一红[1] 郑武[1] 

机构地区：[1]浙江中医药大学附属宁波中医院,宁波315010 [2]宁波市第二医院 [3]宁波市医疗中心李惠利医院

出　　处：《中国针灸》2007年第12期881-885,共5页Chinese Acupuncture & Moxibustion

基　　金：浙江省中医药科研基金计划项目:2004C150

摘　　要：目的:观察和验证中药穴位注射治疗功能性及轻度动脉供血不足勃起功能障碍的临床疗效。方法:采用随机对照方法,将150例功能性及轻度动脉供血不足勃起功能障碍患者分为中药穴位注射组(穴注1组)、注射用水穴位注射组(穴注2组)、回春如意胶囊组(药物组),每组各50例,分别采用丹参注射液、柴胡注射液及注射用水穴位注射关元、足五里、会阴和口服回春如意胶囊,观察各组治疗前后国际勃起功能指数(ⅡEF-5)积分、症候体征、血清生殖内分泌性激素、阴茎海绵体动脉收缩期峰值流速(PSV)的变化情况和整体疗效结果并进行比较。结果:穴注1组总有效率92.0%,穴注2组总有效率84.0%,药物组总有效率66.0%,3组间整体疗效比较差异有显著性或非常显著性意义(P<0.05,P<0.01),穴注1组ⅡEF-5积分、阴茎海绵体PSV治疗前后差异有非常显著性意义(P<0.01),并优于穴注2组与药物组(P<0.05)。3组患者睾酮(T)、卵泡刺激素(FSH)、黄体生成素(LH)及泌乳素(PRL)治疗前后水平变化不明显(P>0.05)。结论:丹参注射液、柴胡注射液穴位注射,穴取关元、足五里、会阴治疗功能性及轻度动脉供血不足勃起功能障碍疗效确切,总体疗效优于注射用水穴位注射及口服回春如意胶囊。Objective To observe and prove clinical therapeutic effect of Chinese drugs acupoint injection therapy on functional and mild arterial low-level blood supply erectile dysfunction（ED）. Methods According to randomized and controlled method,150 cases of functional and arterial low-level blood supply erectile dysfunction were divided into 3 groups, a Chinese drugs acupoint injection group, a saline acupoint injection and a Huichun Ruyi capsules group, 50 patients in each group. They were treated by acupoint injection of Danshen Injection and Chaihu Injection, acupoint injection of saline into Guanyuan （CV 4）, Zuwuli （LR 10） and Huiyin （CV 1）, and oral administration of Huichun Ruyi capsules, respectively. The changes of H EF-5 score, symptoms and signs, serum sexual hormones, Coprus Spongiosum PSV before and after the treatment were observed and compared. Results The total effective rate was 92. 0% in the Chinese drugs acupoint injection group, 84. 0% in the saline acupoint injection group, and 66. 0% in the Huichun Ruyi capsules group, with significant or very significant differences among the 3 groups （P〈0. 05 or P〈0. 01）, and a very significant difference was shown in changes of H EF-5 score and Corus Spongiosum PSV before and after the treatment in the Chinese drugs acupoint injection group （P〈0. 01）, which were better than those in the saline acupoint injection group and the Huichun Ruyi capsules group （P〈0. 05）. No significant changes were found in levels of testosterone （T）, follicule-stimulating hormone （FSH）, luteotropic hormone （LH）, prolactin （PRL） before and after the treatment in the 3 groups （P〉0. 05）. Conclusion Acupoint injection of Danshen Injection and Chaihu Injection has a definite curative effect on functional and arterial low-level blood supply ED. This therapy can raise H EF-5 score obviously and improve Corus Spongiosum PSV. The total effect of Chinese drugs acupoint injection group is better than that of saline acupoint injection or Hu

关 键 词：阴茎勃起/针灸效应 性功能障碍 生理性/针灸疗法 水针 随机对照试验 

分 类 号：R246.1[医药卫生—针灸推拿学]