以天疱疮为首发症状的先天性梅毒临床特点研究  

A Study of the Clinical Features of Congenital Syphilis with Pemphigus Syphilitica

作　　者：李鑫[1] 郑军[1] 安军[2] 

机构地区：[1]天津医科大学第二医院新生儿科,300211 [2]南开大学生命科学学院

出　　处：《中国全科医学》2007年第23期1960-1961,共2页Chinese General Practice

摘　　要：目的了解以天疱疮为首发症状的先天性梅毒的临床特点。方法对2002年1月～2006年6月我院新生儿病房收治的出生即以天疱疮为首发症状的先天性梅毒患儿的病史、临床表现、实验室检查、治疗情况及其母亲情况进行分析。结果所有患儿生后即以天疱疮为首发症状,血清学检测证实为先天性梅毒,患儿的其他临床表现各异。10例患儿中有6例治愈,2例好转,2例死亡。所有患儿母亲血清梅毒检测均为阳性,孕期均未进行常规梅毒检测。结论先天性梅毒患儿可以天疱疮为首发症状,生后即出现特异性皮损,应引起医务人员的高度重视。孕妇产前和孕期的梅毒检测和干预非常重要。Objective To study congenital syphilis with pemphigus syphilitica. Methods The clinical history, and their manifestation and laboratory tests of congenital syphilis infants with pemphigus syphilitlca were analyzed. Their parents were also evaluated. Results All mothers received no prenatal care and had no test for syphilis. Congenital syphilis manifestation varied. The first finding of congenital syphilis infants was pemphigus syphilitica. Conclusion It should be noticiable that pem- phigus syphilitica is the first finding of congenital syphilis. Women with lower educational background and poverty received no prenatal care and had no test for syphilis. It is important for pregnant women to have antenatal care and routine syphilis screening.

关 键 词：天疱疮 梅毒 先天性 婴儿 新生 

分 类 号：R759.15[医药卫生—皮肤病学与性病学]