肌钙蛋白T与CK-MB对急性心肌梗死诊断价值的探讨  

cTnT and CK-MB' tests results analysis with 50 cases of AMI

作　　者：王卫东[1] 高泽斌[1] 许方[1] 范琳琳[2] 

机构地区：[1]大连医科大学第二临床学院检验科,辽宁大连116027 [2]大连医科大学检验系,辽宁大连116027

出　　处：《大连医科大学学报》2007年第6期587-588,593,共3页Journal of Dalian Medical University

摘　　要：[目的]探讨血清肌钙蛋白T(cTnT)和肌酸激酶同工酶(CK-MB)对急性心肌梗死(AM I)的诊断价值。[方法]检测50例因突发胸痛、胸闷及伴有其他临床症状的急诊患者及30例同期非心血管病对照组患者血清肌钙蛋白T和肌酸激酶同工酶的浓度,并进行分析。[结果]患者组与对照组间cTnT、CK-MB值差异均有显著性意义。在检测的50例cTnT升高的患者中,心肌梗死的患者36例,占72%,同期CM-MB阳性率低于cTnT。[结论]cTnT对心肌梗死的诊断有较高的特异性与敏感性,随着发病时间延长CK-MB的敏感性、特异性逐渐升高。[ Objective] To study the value of serum cardiac troponin T （cTnT） and creatine kinase issonzyme MB （ CK - MB） in acute myocardial infarction （AMI）. [ Methods ] The concentrations of cTnT and CK -MB in 50 cases of sudden chest pain, emergency patients of other systems and 30 cases of non - heart and vessel diseases were detected. [ Results] cTnT and CK - MB had evident difference between patients and control group. AMI patients covered 72% in 50 cases of patients whose cTnT increased. The positivity rate of CK -MB was lower than cTnT. [ Conclusion] cTnT has high specificity and sensitivity in the diagnosing AMI. CK -MB＇s sensitivity and specificity are creasing with the length of time of disease.

关 键 词：肌钙蛋白T 肌酸激酶同工酶 急性心肌梗死 

分 类 号：R542.22[医药卫生—心血管疾病]