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机构地区:[1]浙江省温州医学院附属第一医院药剂科,浙江温州325000 [2]浙江省温州医学院附属第一医院骨科,浙江温州325000
出 处:《安徽医药》2007年第12期1078-1079,共2页Anhui Medical and Pharmaceutical Journal
摘 要:目的观察草木犀流浸液片治疗胫腓骨骨折所致肢体肿胀的疗效及不良反应。方法选取胫腓骨骨折患者共90例的临床资料进行回顾性分析,根据用药情况将患者分为治疗组、对照组和联合用药组共3组,每组各30例,分别观察各组肢体肿胀消退的程度和治疗时间。结果草木犀流浸液片组与甘露醇组相比疗效无显著性差异(P>0.05),联合用药组的疗效优于单独用药组。结论草木犀流浸液片具有抗渗出、改善末梢循环、促进创面愈合及明显的消炎镇痛作用,故在治疗胫腓骨骨折所致肢体肿胀方面有应用价值。草木犀流浸液片和甘露醇联合应用,可以治疗中重度肢体肿胀;轻度肢体肿胀患者,单独服用草木犀流浸液片更为方便。Aim To observe the curative effects and side effects of melilotus extract on limb swelling resulting from fractures of tibia and fibula. Methods The clinical data of 90 cases of fractures of tibia and fibula in our department from January ,2006 to June,2007 were analyzed. Patients were averagely divided into three groups according to the use of drugs, i. e, the treatment group, control group and combination therapy group. The extinctive degree of limb swelling and treatment time were observed respectively. Results Melilotus extract and mannitol have the similar effects on extinction of limb swelling( P 〉 0.05 ). The curative effects of group with both melilotus extract and mannitol are superior to groups with melilotus extract or mannitol only. Conclusion Melilotus extract has effects on anti 2 exudation, improving microcirculation,promoting the recovery of wounds and effectively decreasing inflammation and pain. Its side effects are less than other drugs of the same kind, So melilotus extract has the curative effects on limb swelling resulting from fractures of tibia and fibula. Both melilotus extract and mannitol can be used together to treat limb swelling of medium and high degree.
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