伊诺沙星分子印迹聚合物的制备及分子识别性能研究  

Synthesis and research of molecule recognition capability of enoxacin molecularly imprinted polymer

作　　者：连宁[1] 唐江宏[1] 李卫华[1] 贺香红[1] 周全法[1] 

机构地区：[1]江苏技术师范学院化学化工学院江苏省贵金属深加工技术及应用重点建设实验室,江苏常州213001

出　　处：《化学研究与应用》2007年第12期1335-1338,共4页Chemical Research and Application

基　　金：江苏省"青蓝工程"资助项目

摘　　要：以伊诺沙星为印迹分子、甲基丙烯酸为功能单体、季戊四醇三丙烯酸酯为交联剂,合成了对伊诺沙星有较好选择性的印迹聚合物。利用铽敏化荧光,通过静态平衡结合法和Scatchard分析法研究了此印迹聚合物的结合能力和选择性,结果表明印迹聚合物对伊诺沙星有较高的亲和性和选择性。A molecularly imprinted polymer was prepared using enoxaein as the template molecule, methaeylie acid as a monomer and pentaerythritol triaeylate as a cross-linker. The imprinted polymer obtained was investigated in equilibrium binding experiments to evaluate the molecular recognition and binding characteristics of the enoxaein molecularly imprinted polymer using sensitized fluorescence of terbium. Seatehard analysis showed that the imprinted polymer exhibited much higher affinity for enoxaein among the tested eomoounds.

关 键 词：伊诺沙星 分子印迹聚合物 分子识别 

分 类 号：O632.51[理学—高分子化学]