智能化及抗心房颤动起搏器的临床应用  

Clinical use of automatic and anti-AF pacemaker

作　　者：黄建飞[1] 林刚[1] 施林生[1] 管耘园[1] 王世襄[1] 华守明[1] 徐云[1] 

机构地区：[1]江苏省南通市第一人民医院南通大学第二附属医院心内科,南通226001

出　　处：《南通大学学报（医学版）》2007年第5期373-374,377,共3页Journal of Nantong University(Medical sciences)

摘　　要：目的:探讨心房程序起搏治疗阵发性房颤的有效性。方法:对9例阵发性房颤患者置入Vitatron Selection900E(AF2.0)型起搏器,采用自身交叉对照试验,将患者起搏器植入术后1月作普通双腔起搏作为空白对照,术后第2月起根据患者房颤发作不同特点打开相应房颤起搏治疗模式。并记录阵发性房颤事件数、总数、总持续时间及房颤负荷。结果:比较患者术后1月与术后第2、3月的阵发性房颤事件数(10.21±6.37 vs 7.53±4.83)、房颤阵发总数(114.52±97.65vs 86.56±52.17)、房颤总持续时间(5.77±3.62 vs 4.13±2.35)、房颤负荷(24.36%±15.23%vs 18.21%±11.57%)均降低(P均<0.05)。结论:心房程序起搏能够减少阵发性房颤事件的发生,降低房颤负荷,有望成为阵发性房颤药物治疗的重要辅助手段。Objective ：The validity of atrial programmed pacing therapy in paroxysmal atrial fibrillation was observed. Methods ：9 patients who had received the DDDR cardiac pacemaker Selection 900E （AF2.0） were enrolled in this study by crossover designs. The follow-up AF episodes during one month after Pacemaker implantation were vacancy controlled. Different anti-AF preventive pacing algorithms were selected according to the data analysis since 2nd month post implantation. Furthermore, paroxysmal AF events,AF episode total,AF sustained time and AF burden were recorded. Results ：AF episode total, AF sustained time and AF burden during the 2nd and 3rd month were reduced significantly respectively by anti-AF therapy （10.21±6.37 vs 7.53±4.83, 114.52±97.65 vs 86.56±52.17, 5.77±3.62 vs 4.13±2.35, 24.36%±15.23% vs 18.21%± 11.57%, P〈0.05）. Conclusion：Atrial programmed pacing therapy illustrated the efficacy of reducing paroxysmal AF events and AF burden, maybe become an important assistant method in paroxysmal AF therapy.

关 键 词：心房颤动 阵发性 起搏器 心房程序起搏 

分 类 号：R541.75[医药卫生—心血管疾病]