正常赖默—悌曼反应研究:超声波辐射与相转移催化合成方法  

On Normal Reimer-Tiemann Reaction Under Ultr asonic Irradiation Techique and With Phase-Transfer Catalysis Metthod

作　　者：肖敏[1] 陈晖 梁本熹[1] 吴晓平 村松Y 松本S 李志良[1] 

机构地区：[1]湖南大学化学化工院,长沙410082 [2]日本国立技科大学 [3]早稻田大学

出　　处：《吉首大学学报》1997年第2期10-14,共5页

基　　金：国家自然科学基金;日本政府文部省和国家教委及机械部资助

摘　　要：系统研究了正常及反常赖政－悌曼反应（NormalorAbnormalReliner－TiemannReavction，NRYorART）；研究了相转移住化方法和超声波辐射技术及其在正常Reliner—Tiemann（NRT）反应中的应用，从而使反应条件温和，效率增加，对邻比大，时间缩短，取得较好收效。Systematic investigation was made on normal and abnormal Reimer-tiemann (NRT,ART) reactions and on appications of phase-transfer catalysis (PTC) and ultras onicirradi-ation (USI) techniques to organic synthesis. In this paper, phase-transfercatalysis (PTC)methid and ultrasonic irradiation technique and their combination wereused for performingthe normal Reimer-Tiemann (NRT) reaction. The introduction of thecombination tech-nique took serval advantages: (1) the NRT reaction occours more easily which can be per-formed at room-temperrature (at about 30℃) ; (2) the total yields of twohydroxy-benzaldehydes arises to be higher; (3) the amount of para-substituted priductincreases by alarge scale; (4) the reaction time becomes much shorter.These results show a good applicable prospect of PTC and USI techniques in organnicsynthesis.

关 键 词：苯酚 超声波辐射 相转移催化 R-T反应 羟基芳醛 

分 类 号：O625.312[理学—有机化学]