(22E,24S)-2α,3α-二羟基-5α-豆甾烷-22-烯-6-酮的环氧化及其立体异构体的分离  

Epoxidation of (22E,24S)-2α,3α-Dihydroxy-5α-Stigmastan-22-En-6-One and Separation of Epoxide Isomers

作　　者：尹永洙[1] 李熙峰[1] 田官荣[1] 

机构地区：[1]延边大学理学院化学系,吉林延吉133002

出　　处：《延边大学学报（自然科学版）》2007年第4期264-266,共3页Journal of Yanbian University（Natural Science Edition）

摘　　要：用过氧乙酸把(22E,24S)-2α,3α-二羟基-5α-豆甾烷-22-烯-6-酮转化成相应的环氧化物,用液相色谱分离两种立体异构体并用核磁共振数据确定了结构,比较了3种过氧酸的反应性能.The （22E, 24S）-2α, 3α-dihydroxy-5α-stigmastan-22-en-6-one was transformed corresponding to epoxide by the peroxyacetic acid. The two epoxide isomers have been separated by liquid chromatography and their structures were identified by NMR. The activity of three peroxyacid were discussed.

关 键 词：过氧乙酸 (22E 24S)-2α 3α-二羟基-5α-豆甾烷-22-烯-6-酮 环氧化 

分 类 号：O622.5[理学—有机化学]